Results 151 to 160 of about 1,973,336 (299)
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
An Experimental Investigation of Fairness and Reciprocal Behavior in a Triangular Principal'-Multiagent Relationship. [PDF]
A laboratory investigation of a simple agency model that allow to study how the principal's fairness affects the attitude towards cooperation between two interdependent agents performing a simple production task.principal-agent theory; prisoner's dilemma;
Alessandro Rossi, Massimo Warglien
core
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Emprego de indicadores socioeconômicos na avaliação financeira de cooperativas agropecuárias
Economia Aplicada, 2001 Most ofthe Brazilian cooperatives are concerned with evaluating periodically only its economical and financial environment, forgetting to consider thatthis kind ofenterprise is also a society ofpeople which have one main purpose: the assistance to its ...
Alexandre Hattnher Menegário +1 more
doaj
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Broiler farming and antibiotic use through an agency theory lens. A case study from West Bengal, India. [PDF]
PLoS OneHennessey M +8 more
europepmc +1 more source
Relational Identities and Other-Than-Human Agency in Archaeology
, 2018 Relational Identities and Other-than-Human Agency in Archaeology explores the benefits and consequences of archaeological theorizing on and interpretation of the social agency of nonhumans as relational beings capable of producing change in the world ...
Harrison-Buck, Eleanor, Hendon, Julia A.
core
Aging and Cancer, EarlyView.Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Traceability in the U.S. Food Supply: An Application of Transaction Cost Analysis [PDF]
Suboptimal supply of food and agricultural traceability is framed in a transaction cost analysis. We propose a model that considers the variables of opportunism potential, agency costs, uncertainty, asset specificity, frequency, and transaction costs ...
Bravo, Jesus, Wang, Chao-shih
core +1 more source