Results 121 to 130 of about 724,398 (302)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang   +15 more
wiley   +1 more source

Ekonomi politik media: analisis keberpihakan pemberitaan Sindonews pada calon presiden pasca debat 1 calon presiden

open access: yesLektur
Abstrak Penelitian ini bertujuan menganalisis keberpihakan pemberitaan Sindonews terhadap calon presiden pasca debat pertama melalui pendekatan ekonomi politik media dan menggunakan Teori Agenda Setting oleh Maxwell McCombs dan Donald Shaw.
Azam Muzafarudin Arkham
doaj   +1 more source

Institutional theory and legislatures [PDF]

open access: yes, 2008
Institutionalism has become one of the dominant strands of theory within contemporary political science. Beginning with the challenge to behavioral and rational choice theory issued by March and Olsen, institutional analysis has developed into an ...
Judge, David
core  

AutomataGPT: Transformer‐Based Forecasting and Ruleset Inference for Two‐Dimensional Cellular Automata

open access: yesAdvanced Science, EarlyView.
We introduce AutomataGPT, a generative pretrained transformer (GPT) trained on synthetic spatiotemporal data from 2D cellular automata to learn symbolic rules. Demonstrating strong performance on both forward and inverse tasks, AutomataGPT establishes a scalable, domain‐agnostic framework for interpretable modeling, paving the way for future ...
Jaime A. Berkovich   +2 more
wiley   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

Opini Publik, Agenda Setting, dan Kebijakan Publik

open access: yesJurnal Komunikasi, 2011
This article is based on the theory that public opinion has important role in the democratic system. In this system, government should be responsive to public opinion that has rised in society, in which that is the only way for government to be sustained.
Puji Rianto
doaj  

Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices

open access: yesAdvanced Science, EarlyView.
This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee   +4 more
wiley   +1 more source

Theoretical multiplicity for the governance of transitions. The energy producing greenhouse case [PDF]

open access: yes
Transition management, as a theory of directing structural societal changes towards sustainable system innovations, has become a major topic in scientific research over the last years.
Dewulf, A., Termeer, C.J.A.M.
core  

Political attention to environmental issues: Analyzing policy punctuations in the Netherlands [PDF]

open access: yes, 2009
One of the most dramatized features in Al Gore's movie The Inconvenient Truth is the effects of a rising sea-level in the Netherlands. The film is an example of how the mobilization of bias in the Netherlands resulted in sudden high levels of attention ...
Breeman, G.E., Timmermans, A.
core   +1 more source

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