Results 41 to 50 of about 809,951 (281)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Resumen ejecutivo del informe de progreso 2022 de la estrategia de desarrollo sostenible 2030 [PDF]

open access: yes, 2022
Resumen: El pasado 25 de septiembre se cumplieron siete años desde que la Asamblea General de las Naciones Unidas aprobó la Agenda 2030 para el Desarrollo Sostenible y, desde entonces, son muchas las áreas en las que se han logrado avances significativos
España. Ministerio de Derechos Sociales y Agenda 2030. Secretaría de Estado para la Agenda 2030
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Qué hacer con el sistema judicial? [PDF]

open access: yes, 1999
Se incluye en el CD-ROM: Agenda : Perú; la propuesta más completa para el siglo XXI ...
Eguiguren Praeli, F.J., Agenda: Perú
core   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Categorization Rules and Disambiguation Rules

open access: yes
31 Categorization Rules and Disambiguation ...
ChiLat, Agenda
core   +2 more sources

Rule of law y rule by law: el caso de la inversión extranjera en Guangdong y Jiangsu (China)

open access: yesEstudos Internacionais, 2020
¿Por qué provincias similares tienen distinta estabilidad en sus flujos de inversión extranjera? La investigación compara las provincias de Guangdong y Jiangsu en la República Popular China y discute porqué estas provincias de similares características ...
Mariano Mosquera
doaj   +1 more source

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