Results 141 to 150 of about 1,981,748 (306)
Advanced Materials, EarlyView.Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode +16 more
wiley +1 more source
Antropologia da Ciência, Educação Ambiental e Agenda 21 Local
Educação & Realidade, 2008 O artigo tem como objetivo apresentar uma contribuição da Antropologia da Ciência à Educação Ambiental. Para tanto, discute a dicotomia objeto-sujeito à luz da noção de simetria entre natureza e cultura, tal como apresentada por Bruno Latour.
Fátima Braga Branquinho +1 more
doaj
Advanced Materials, EarlyView.A novel immunotherapeutic strategy combines injectable, adjuvant‐loaded hydrogels with externally controlled histotripsy to create immune‐priming sites within tumors. This approach generates millimeter‐sized immune‐activated lesions with flexible, patient‐tailored treatment scheduling, enabling precise immune activation through tumor ablation‐mediated ...
Sung Hoon Kim +9 more
wiley +1 more source
Superionic Amorphous Li2ZrCl6 and Li2HfCl6
Advanced Materials, EarlyView.Amorphous Li2HfCl6 and L2ZrCl6 are shown to be promising solid‐state electrolytes with predicted ionic conductivities >20 mS·cm−1. Molecular dynamics simulations with machine‐learning force fields reveal that anion vibrations and flexible MCl6 octahedra soften the Li coordination cage and enhance mobility. Correlation between Li‐ion diffusivity and the
Shukai Yao, De‐en Jiang
wiley +1 more source
Environmentally sustainable houshold consumption: From aggregate environmental pressures to indicators for priority fields of action [PDF]
During the UNCED conference in Rio de Janeiro 1992 unsustainable consumption and production patterns were identified as one of the key driving forces behind theunsustainable development of the world (Agenda 21, chapter 4).
Lorek, Sylvia, Spangenberg, Joachim H.
core
Nanoporous Microelectrodes for Neural Electrophysiology Recordings in Organotypic Culture
Advanced Materials Technologies, EarlyView.The highly porous microelectrodes have been designed and printed on culture membranes, allowing to record electrophysiological neural activity for rodent brain slices. To keep the biocompatible nanoporous structure, the microelectrodes and insulative layer are fabricated on the bottom of culture membranes with only small connector pads added on the top.
Petro Lutsyk +3 more
wiley +1 more source
Advanced Materials Technologies, EarlyView.Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner +10 more
wiley +1 more source
Agenda 21 The First Five Years. Implementation of Agenda 21 in the European Community [PDF]
, 1997 core +2 more sources
Advanced Materials Technologies, EarlyView.This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane +4 more
wiley +1 more source