Results 221 to 230 of about 1,981,748 (306)

Ferrara: agenda 21 Locale ed il Piano Urbanistico [PDF]

, 2005
Bini, G.
core  

Sirt3 Genetically Engineered Apoptotic Bodies Alleviate Skeletal Aging by Limiting Aggravated NLRP3 Inflammasome Activation of Senescent Macrophages

Advanced Science, EarlyView.
The senescence of macrophages leads to a decrease in the expression of Sirtuin3 (Sirt3), which in turn aggravates the NLRP3 inflammasome activation and IL‐1β secretion, thereby promoting the aging‐related osteoporosis. Sirt3‐enriched apoptotic bodies (ABs‐Sirt3) generated through genetic editing approaches can alleviate skeletal aging by targeting ...
Yanglin Wu, Shifeng Ling, Jiayi Mao, Hongyi Wang, Bo Wang, Zhenjia Che, Wenguo Cui, Ming Cai   +7 more
wiley   +1 more source

Toward a "green" brain health agenda: establishing short- and long-term goals for the field of neurology in a changing climate. [PDF]

Front Neurol
Trahair ED, Dalapati T, Levinson D, Linares AR, Reuben A, Bedlack R.   +5 more
europepmc   +1 more source

A Non‐Mitophagy Activity of BNIP3L/NIX in Amygdala Glutamatergic Neurons is Essential for Contextual Fear Memory Formation

Advanced Science, EarlyView.
Contextual fear conditioning induces BNIP3L‐dependent mitochondrial fission in glutamatergic neurons of the BLA, independently of mitophagy. Loss of BNIP3L elevates Drp1Ser637 phosphorylation, thereby suppressing mitochondrial fission, compromising ATP production, and attenuating excitatory synaptic transmission.
Xingxian Zhang, Xinlei Mo, Xinyu Zhou, Xiaoliang Liu, Guizhi Li, Songhui Hu, Yangyang Lu, Chenze Zhu, Jinxi Feng, Zhitong Chen, Weiwei Hu, Yihui Cui, Zhong Chen, Xiangnan Zhang   +13 more
wiley   +1 more source

An Agenda for Public Health Diplomacy in an Age of Populism. [PDF]

Public Health Rev
McKee M, Figueras J, Kalediene R, Joshi A, El-Mohandes A, Otok R, Magaña L, Marchandise C, Barros H.   +8 more
europepmc   +1 more source

Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy

Advanced Science, EarlyView.
A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao, Shan Qiao, Jie Bai, Jingjing Zhang, Zhiqin Xi, Zhenzhen Li, Xuelin Zhan, Ying Zhang, Xiaotong Yu, Yao Chen, Yijin Liu   +10 more
wiley   +1 more source

Gender Equality Stock-Take into the WHO Regional Office for Africa's Transformation Agenda: Progress and Opportunities. [PDF]

J Healthc Leadersh
Chingarande SD, Rwamatwara E, Kithinji D, Nsarhaza K.   +3 more
europepmc   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

Bridging the Gap Between Research Agendas and Practice: Insights from a Novel Evaluation Method

Powell AR, Zuniga YAB, Eksteen S, Tomlinson M, Dartnall E.   +4 more
europepmc   +1 more source

Not forgetting the humanitarian contexts in the fight against antimicrobial resistance: Operational-driven reflection on knowledge and research gaps by Médecins Sans Frontières. [PDF]

PLOS Glob Public Health
Garcia-Vello P, Naim C, Langendorf C, Shortall C, Jasovský D, Gomez FG, Hanna DA, Khalife M, Broomand A, Wagan J, Poupard M, Adjaho I, Baidjoe A, Kanapathipillai R, Farra A.   +14 more
europepmc   +1 more source