Results 41 to 50 of about 28,257 (295)

A brief look on Agenda - setting theory nowadays

open access: yesPauta Geral - Estudos em Jornalismo, 2020
Professor Maxwell McCombs began his career as a journalist in the 1960s, as a reporter for the New Orleans Times. A decade later, McCombs, in partnership with Donald Shaw, developed one of his major theories -the agenda-setting hypothesis, now considered a theory, which reflects on the influence of the mass media in ...
Fernanda Ferreira   +2 more
openaire   +2 more sources

Web Portal Feels Like Home. Applying Agenda-setting Theory to Internet-based Media and their Influence on Cybersociety [PDF]

open access: yes, 2005
The progressive process of internetization leads the audience little by little to setting aside traditional media of today's every day: dailies, radio and television.
M. Pregowski
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Agenda-setting theory on social media: Does the algorithm control information? [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini
In modern society, which witnesses an expansive increase of digital technologies in everyday life, digital literacy has become almost essential for the functioning of individuals, communities, institutions, states, and interpersonal relationships.
Šmigić Jovana N.
doaj   +1 more source

Agenda-Setting – Unconfirmed Theory or Real Phenomenon?

open access: yes, 2012
Each day the media filters information, making a set hierarchy of importance. Media agenda has a great influence on the point of view of most of the viewers who get most of their world knowledge from mass media.
Joanna Wieczorek, Wieczorek, Joanna
core   +1 more source

Origins and development of the agenda-setting theory in Communication: trends in Spain (2014-2019) [PDF]

open access: yes, 2020
The core hypothesis of the theory of agenda setting is that there is a process of transfer of salience from the media agenda to the public agenda. Since its original conception in the early 1970s, the explanatory model of ‘issue-agenda setting’ (first ...
McCombs, Maxwell   +2 more
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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