Results 181 to 190 of about 29,338,642 (259)

Rules of Engagement: A Guide to Developing Agent-Based Models. [PDF]

Methods Mol Biol, 2022
Griesemer M, Sindi SS.
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Astrocyte Reprogramming Drives Tumor Progression and Chemotherapy Resistance in Agent-Based Models of Breast Cancer Brain Metastases. [PDF]

Bull Math Biol
Kaur R, Barker-Clarke R, Dhawan A.
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

An analysis of spatial and temporal uncertainty propagation in agent-based models. [PDF]

Philos Trans A Math Phys Eng Sci
Gamal Y, Heppenstall A, Strachan W, Colasanti R, Zia K.   +4 more
europepmc   +1 more source

Agent-based models of human response to natural hazards: systematic review of tsunami evacuation. [PDF]

Nat Hazards (Dordr), 2023
Mls K, Kořínek M, Štekerová K, Tučník P, Bureš V, Čech P, Husáková M, Mikulecký P, Nacházel T, Ponce D, Zanker M, Babič F, Triantafyllou I.   +12 more
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Surrogate modeling of Cellular-Potts agent-based models as a segmentation task using the U-Net neural network architecture. [PDF]

PLoS Comput Biol
Comlekoglu T, Toledo-Marín JQ, Comlekoglu T, DeSimone DW, Peirce SM, Fox G, Glazier JA.   +6 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Bridging behavioral theory and household energy decisions: enhancing agent-based models with behavioral analysis. [PDF]

Front Psychol
Rietkerk-van der Wijngaart M, de Jager L, Scholz G, Chappin E, de Vries G.   +4 more
europepmc   +1 more source