Results 201 to 210 of about 11,927,890 (342)

A hybrid PKPD agent-based model of the tumour immune interaction: effects of anti-cancer combination therapy. [PDF]

J Pharmacokinet Pharmacodyn
Truong VT, Lythe G, Vicini P, Yates JWT, Dubois VFS.   +4 more
europepmc   +1 more source

An agent-based model for financial vulnerability

Journal of Economic Interaction and Coordination, 2017
Richard M. Bookstaber, M. Paddrik, B. Tivnan   +2 more
semanticscholar   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

An agent-based model of metabolic signaling oscillations in Bacillus subtilis biofilms. [PDF]

PLoS Comput Biol
Mulder OJ, Peters Kostman M, Almodaimegh A, Edge MD, Larkin JW.   +4 more
europepmc   +1 more source

An agent-based model for diffusion of electric vehicles

, 2017
A. Kangur, W. Jager, R. Verbrugge, M. Bockarjova   +3 more
semanticscholar   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Simulating nationwide coupled disease and fear spread in an agent-based model. [PDF]

Sci Rep
Kitson J, Alexander PC, Tuccillo J, Butts DJ, Brelsford C, Bhatele A, Del Valle SY, Germann TC.   +7 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Adapting Sexual Behavior Survey Data to Parameterize an Agent-Based Model of Human Papillomavirus (HPV) Transmission. [PDF]

Med Decis Making
Spencer JC, Burger EA, Portnoy A, Campos NG, Regan MC, Sy S, Kim JJ.   +6 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source