Results 201 to 210 of about 29,035,453 (305)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Capturing Argument in Agent-Based Models. [PDF]

Topoi (Dordr)
Assaad L, Fuchs R, Phillips K, Schöppl K, Hahn U.   +4 more
europepmc   +1 more source

Institutional modelling: Adding social backbone to agent-based models. [PDF]

MethodsX, 2022
Ghorbani A.
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

BIWT: a bioinformatics walkthrough for embedding spatial multiomics in agent-based models for virtual cells. [PDF]

Bioinformatics
Bergman DR, Johnson JAI, Naji M, Booth M, Lima da Rocha H, Deshpande A, Sidiropoulos DN, Lopez-Vidal T, Heiland R, Kagohara LT, Anders RA, Zheng L, Jaffee EM, Stein-O'Brien G, Macklin P, Fertig EJ.   +15 more
europepmc   +1 more source

Feedback Loops in Opinion Dynamics of Agent-Based Models with Multiplicative Noise. [PDF]

Entropy (Basel), 2022
Djurdjevac Conrad N, Köppl J, Djurdjevac A.   +2 more
europepmc   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Delayed skeletal muscle repair following inflammatory damage in simulated agent-based models of muscle regeneration. [PDF]

PLoS Comput Biol, 2023
Khuu S, Fernandez JW, Handsfield GG.
europepmc   +1 more source

The ABM Template Models -- A Reformulation with Reference Implementations [PDF]

This paper refines a well-known set of template models for agent-based modeling and offers new reference implementations. It also addresses issues of design, flexibility, and ease of use that are relevant to the choice of an agent-based modeling platform.
Alan G. Isaac
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source