Results 111 to 120 of about 2,565,092 (318)

Immunoprevention of non-viral cancers: challenges and strategies for early intervention

Cancer Cell International
While the effects of cancer vaccines have been extensively studied in the therapeutic setting, research has been more limited in the areas of cancer prevention and interception.
Kajal Biswas, Lillian S. Kuo, Robert H. Shoemaker, Altaf Mohammed   +3 more
doaj   +1 more source

Performance of Improved Bell Pepper Cultivars in Southern Georgia for Mature Green Fresh Market Production

HortTechnology
Three research trials were performed over two spring seasons to assess the performance of bell pepper (Capsicum annuum) cultivars in southern Georgia, USA.
Manisha Kumari, Bhabesh Dutta, Timothy Coolong, Ty Torrance, Justin Shealey, Joshua Dawson, Theodore McAvoy   +6 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Acetate bridged zinc(II) complexes with 5-bromo-2-[(2-ethylaminoethylimino)methyl]phenol: Syntheses, X-ray crystal structures and antibacterial potential

Results in Chemistry
Three new acetate bridged polynuclear zinc(II) complexes [ZnL(μ2-η1:η1-OAc)]n (1), [Zn3L2(μ2-η1:η1-OAc)2(μ2-η2:η0-OAc)2] (2) and [Zn2L(μ2-η1:η1-OAc)2(NCS)] (3), were first synthesized from 5-bromo-2-[(2-ethylaminoethylimino)methyl]phenol (HL) with ...
Chengbin Sun, Guoze Wang, Peng Wang, Xiuhua Wen, Wei Kan, Bing Zhao   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Agent-Based Support for Human/Agent Teams

, 2000
In this paper, we present an interface agent, MokSAF, which facilitates time-critical team-planning tasks for teams of both humans and heterogeneous software agents.
Hahn, Susan, Sycara, Katia, Terri L. Lenox, Katia Sycara, Payne, Terry R., Lenox, Terri L., Michael Lewis, Susan Hahn, Lewis, Michael, Terry R. Payne   +9 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A formal framework for the semantics of agent interactions

, 2005
Although informative, the semantic definition proposed for the most standard agent communication language (FIPA ACL 1997) is complicated and contentious, while published inter-action protocols (IPs) tend to be ambiguous, incomplete, and unverified with ...
Jennings, N. R., Cunningham, J., Cunningham, J, Paurobally, S, Paurobally, S., Jennings, NR   +5 more
core  

Service fusion in mobile contexts

, 2010
Service provision for mobile users poses several challenges for those managing enterprise information systems. Some of these are ubiquitous, for example, privacy and security. Others give rise to integration and interoperability issues.
Michael J. O’Grady, Jun Miao Shen, O'Hare, G. M. P. (Greg M. P.), Gregory M. P. O’Hare, Shen, J. M., O'Grady, Michael J., O\u27Grady, Michael J., O\u27Hare, G. M. P. (Greg M. P.)   +7 more
core   +1 more source