Results 201 to 210 of about 28,155 (267)

Agent-to-Agent Communication

Agent-to-agent communication is increasingly moving beyond the human-visible transcript: while classical multi-agent reinforcement learning allows agents to invent discrete symbols or continuous vectors, contemporary large-language-model systems increasingly explore embeddings, hidden states, and key-value caches as direct communication media.
openaire   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Unraveling the complex web of acute kidney injury: pathways, biomarkers, and future directions. [PDF]

J Bras Nefrol
Zha C, Qi Y, Yang, Li G, He Z, Xu D, Li J.   +6 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

From Cholesterol Metabolism to Comprehensive Lipid Management and Crosstalk of Inflammation: Expanding the Frontiers of Cardiovascular Prevention. [PDF]

Arq Bras Cardiol
Vilela E, Bettencourt N.
europepmc   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

National Primary Care Policy (2017) and the roles of community health workers. [PDF]

Rev Bras Enferm
Dias JR, Acioli S, Corrêa VAF, Souza IL, Rafael RMR, Rodrigues PHA, Bohusch G.   +6 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

[Podiatric health as a strategy for equity and prevention from primary care]. [PDF]

Aten Primaria
Tovaruela-Carrión N, López-López D, Gómez-Salgado J.   +2 more
europepmc   +1 more source

[Work, mental health, quality of life, and social support of community health agents during and after the COVID-19 pandemic under a gender perspective]. [PDF]

Cad Saude Publica
Albuquerque GA, Ferreira RGLA, Aguiar ASW, Campelo ILB, Dias MSA, Vieira-Meyer APGF.   +5 more
europepmc   +1 more source