Results 131 to 140 of about 12,540 (279)

The Production of Agglutinins in Response to Antigens of Ascaris Lumricoides Var. Suum

open access: yes, 1962
Studies of immunological reactions with Ascaris lumbricoides var. suum have been carried out by a number of investigators involving in vitro and in vivo tests. As far as can be determined agglutinin antibodies have not been demonstrated.
Prouty, James Lee
core  

A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend 3D cardiomyocyte segmentation enables comprehensive analyses of myocardial microstructure in health and disease; however, it is technically demanding. We present an open‐source toolkit for this task, which reduces challenges associated with sample preparation, image restoration, segmentation and proofreading.
Joachim Greiner   +6 more
wiley   +1 more source

Low Prevalence of Brucella agglutinins in Blood Donors in Central Province of Iran

open access: yesIranian Journal of Microbiology, 2013
Background and Objective: Brucellosis is a zoonotic disease of worldwide distribution and has great economic importance. Despite its control in many countries, it remains endemic in Iran. Brucellosis was investigated in many high risk occupational groups;
Masoomeh Sofian   +8 more
doaj  

An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Stable, responsive pacemaking in the sinoatrial node is driven by the activity of the funny current (membrane clock), interplay of calcium cycling and release from the sarcoendoplasmic reticulum with depolarising sodium‐calcium exchange current (calcium clock). With increasing age, key proteins associated with calcium cycling are
Sandra A. Jones   +2 more
wiley   +1 more source

The ultrarapid delayed rectifier potassium current has important functional role in the repolarization reserve of canine and human ventricular muscle

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend The ultrarapid delayed rectifier potassium current (IKur) has long been considered an atrial‐specific current with no functional role in the ventricles, despite evidence of its expression in ventricular myocytes. In the present study we challenged this prevailing concept and investigated the potential role of IKur in ventricular ...
Alaa Amin E. Abdelmagid   +17 more
wiley   +1 more source

Diving into the unknown: Evidence of enhanced skeletal muscle lactate efflux potential and blood–muscle exchange in competitive breath‐hold divers

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Competitive breath‐hold divers exhibit skeletal muscle characteristics indicative of enhanced blood‐muscle exchange capacity and increased lactate efflux potential. Top left: Participant characteristics, matched for age, height, body mass, and maximal oxygen uptake (V̇O2max${\dot{\mathrm{V}}}\rm{O}_{\rm{2max}}$).
Antonis Elia   +7 more
wiley   +1 more source

Plasma exosomal miR‐339‐3p promotes myocardial remodeling in chronic heart failure by regulating USP25‐mediated DDX58 deubiquitination

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 3, September 2026.
In the patients of chronic heart failure (HF), miR‐339‐3p derived from plasma exosomes can target ubiquitin‐specific protease 25, inhibiting its K48‐linked deubiquitination modification of DDX58, leading to increased ubiquitination and degradation of DDX58.
Guoqiang Jing, Ting Xu, Yuhong Ma
wiley   +1 more source

Safety and Effectiveness of Sutimlimab in Cold Agglutinin Disease: A Real‐World International Experience

open access: yesAmerican Journal of Hematology, Volume 101, Issue 7, Page 1597-1604, July 2026.
ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo   +38 more
wiley   +1 more source

Feasibility Study of Combined Systemic Therapy and Carbon‐Ion Radiotherapy for Hepatocellular Carcinoma Patients

open access: yesCancer Medicine, Volume 15, Issue 7, July 2026.
ABSTRACT Background Recent advances in systemic therapy, including tyrosine kinase inhibitors (TKIs) and immune checkpoint inhibitors (ICIs), have improved outcomes for hepatocellular carcinoma (HCC) and enabled downstaging strategies that allow subsequent local treatments. Carbon‐ion radiotherapy (CIRT) can provide excellent tumor control with minimal
Daijiro Kobayashi   +6 more
wiley   +1 more source

Quantifying Protein–Glycan Interactions Using Native Mass Spectrometry

open access: yesMass Spectrometry Reviews, Volume 45, Issue 4, Page 800-828, July/August 2026.
ABSTRACT Interactions between glycan‐binding proteins (GBPs) and carbohydrates (glycans) are essential to many biological processes relevant to human health and disease. For most GBPs, however, their glycan interactome—the repertoire of glycans recognized and their specificities—is poorly defined.
Duong T. Bui   +4 more
wiley   +1 more source

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