Results 1 to 10 of about 1,491 (78)
Self-Consistent Field Modeling of Bottle-Brush with Aggrecan-like Side Chain [PDF]
BiomimeticsBottle-brush polymers with aggrecan-like side chains represent a class of biomimetic macromolecules that replicate key structural and functional features of natural complexes of aggrecans with hyaluronic acid (HA) which are the major components of ...
Ivan V. Mikhailov +3 more
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Frontiers in Genetics, 2021 Short stature is a frequent disorder in the pediatric population and can be caused by multiple factors. In the last few years, the introduction of Next Generation Sequencing (NGS) in the molecular diagnostic workflow led to the discovery of mutations in ...
Mara Giordano +2 more
exaly +3 more sources
Friction, 2022 Synovial fluid is made up of various biomacromolecules, including hyaluronic acid, aggrecans, lubricins, and phosphatidylcholine lipid, which are assembled onto the surface of articular cartilage in a gel state.
Guoqiang Liu +6 more
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Multi-omics in thoracic aortic aneurysm: the complex road to the simplification
Cell & Bioscience, 2023 Background Thoracic aortic aneurysm (TAA) is a serious condition that affects the aorta, characterized by the dilation of its first segment. The causes of TAA (e.g., age, hypertension, genetic syndromes) are heterogeneous and contribute to the weakening ...
Sara Rega +10 more
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Stem Cell Research & Therapy, 2017 Background The umbilical cord is becoming a notable alternative to bone marrow (BM) as a source of mesenchymal stromal cells (MSC). Although age-dependent variations in BM-MSC are well described, less data are available for MSC isolated from Wharton’s ...
Léonore Avercenc-Léger +10 more
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Neural Plasticity, 2016 Perineuronal nets (PNNs) are lattice-like extracellular matrix structures composed of chondroitin sulfate proteoglycans (CSPGs). The appearance of PNNs parallels the decline of neural plasticity, and disruption of PNNs reactivates neural plasticity in ...
Shinji Miyata, Hiroshi Kitagawa
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AntioxidantsDelphinidin (Delp), a natural antioxidant, has shown promise in treating age-related ailments such as osteoarthritis (OA). This study investigates the impact of delphinidin on intervertebral disc degeneration (IVDD) using human nucleus pulposus cells ...
Md Entaz Bahar +5 more
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A comprehensive review of nanotechnology based drug delivery systems for osteoarthritis treatment
Nanotechnology ReviewsThe complex etiology and short-term positive effects of treatments for osteoarthritis (OA) remain a significant challenge globally. The lack of approved disease-modifying OA drugs (DMOADs) and the rapid clearance of intra-articular (IA) injections limit ...
Adikari Clawdia +4 more
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Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2017 Background and Objectives: Due to the lack of blood vessels in cartilage tissue, its damage is not repairable. This study was conducted to investigate the effect of soy isoflavone on proliferation and differentiation of adipose-derived mesenchymal stem ...
Fatemeh Bamdadpasand Shekarsarayi +2 more
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Immunological Roles of Fibroblast-Like Synoviocyte Cells in Rheumatoid Arthritis [PDF]
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī YazdIntroduction: Fibroblast-like synoviocytes (FLS), also known as synovial fibroblasts or type B synoviocytes, are the primary cells responsible for the structure of the synovial lining.
Mohammad Reza Royaei +1 more
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