Amino Acid Metabolism in Health and Disease
This graphical abstract delineates the multifaceted role of amino acid metabolism in health and disease. It illustrates how amino acids sustain physiological homeostasis across the liver, kidney, brain, heart, intestine, muscle, skeleton, and immune system.
Zhiwei Su +7 more
wiley +1 more source
The High‐Intensity Zone: A Dynamic Inflammatory Hub in Lumbar Disc Degeneration
The HIZ, a dynamic inflammatory hub in lumbar disc degeneration, links inflammation‐degeneration‐pain; integrating advanced diagnostics and targeted therapies offers precise management for discogenic low back pain. ABSTRACT The lumbar intervertebral disc high‐intensity zone (HIZ), a focal hyperintensity within the annulus fibrosus on T2‐weighted ...
Qi Zhou +6 more
wiley +1 more source
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley +1 more source
Cabozantinib prevents AGEs-induced degradation of type 2 collagen and aggrecan in human chondrocytes. [PDF]
Dong Y, Lin L, Ji Y, Cheng X, Zhang Z.
europepmc +1 more source
The mechanical properties of articular cartilage are associated with the extracellular matrix network of type II collagen and the proteoglycan, aggrecan, which in combination provide the tensile, shear, and compressive stiffness of the tissue. While the collagen network mainly provides resistance to tensile and shear deformation, aggrecan enmeshed ...
openaire +1 more source
Biomechanical analysis of mandibular cartilage defect regeneration after implantation of human umbilical cord mesenchymal stem cells and a platelet rich fibrin scaffold: an experimental animal study. [PDF]
Sumarta NPM +5 more
europepmc +1 more source
Efficacy of Combined <i>Hericium erinaceus</i> Mycelium and Undenatured Type II Collagen in Reducing Osteoarthritis Progression in a Preclinical Animal Model. [PDF]
Lee KT +10 more
europepmc +1 more source
Evaluating anticancer activity of emodin by enhancing antioxidant activities and affecting PKC/ADAMTS4 pathway in thioacetamide-induced hepatocellular carcinoma in rats. [PDF]
Hassan HM +5 more
europepmc +1 more source
Size-dependent alterations in phrenic motor neuron perineuronal nets following cervical spinal hemisection. [PDF]
Cheung SW +5 more
europepmc +1 more source
Avenanthramide C and chondroitin sulphate promote chondrogenic differentiation of adipose-derived mesenchymal stem cells. [PDF]
Sun P +3 more
europepmc +1 more source

