Results 211 to 220 of about 448,373 (268)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Compressive Stress-Strain Relationship of Recycled Coarse Aggregate Concrete After Sulfate Corrosion and High Temperature. [PDF]

Materials (Basel)
Cai Z, Wu J, Zhao X, Lu X, Zhang L, Wang Y, Luan H.   +6 more
europepmc   +1 more source

Damage mechanism investigation on fiber reinforced recycled cement aggregate concrete in a cold region. [PDF]

Sci Rep
Li W, Li Z, Xu W, Ji Y.
europepmc   +1 more source

Experimental study on grouting diffusion mechanism of fractured rock. [PDF]

Sci Rep
Zhang C, Li D, Zhang X, Cong Y, Huang Y, Zhang H, Huang Y, Liu Q, Gao X.   +8 more
europepmc   +1 more source

Aggregation-Tuned Charge Transport and Threshold Voltage Modulation in Poly(3-hexylthiophene) Field-Effect Transistors. [PDF]

Materials (Basel)
Park B.
europepmc   +1 more source

Physics-guided machine learning framework for RCA concrete by experimental database, modelling, and statistical validation. [PDF]

Sci Rep
Mohamud MA, Alasiri MR, Özdöner N, Yıldızel SA, Özkılıç YO.   +4 more
europepmc   +1 more source