Results 91 to 100 of about 2,715,691 (402)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Application of functionally graded materials for severe plastic deformation and smart materials: experimental study and finite element analysis [PDF]
Functionally graded materials (FGMs) refer to the composite materials where the compositions or the microstructures are locally varied so that a certain variation of the local material properties is achieved.
Jamian, Saifulnizan
core
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
The chemical composition of mineral trioxide aggregate
Mineral trioxide aggregate (MTA) is composed of Portland cement, with 4:1 addition of bismuth oxide added so that the material can be detected on a radiograph. The cement is made up of calcium, silicon and aluminium. The main constituent phases are tricalcium and dicalcium silicate and tricalcium aluminate. There are two commercial forms of MTA, namely
openaire +3 more sources
ACI Technical Report: Initial Measures Derived from Census [PDF]
The decennial census provides a wealth of information about communities that has been mined by social scientist for decades. The purpose of this technical report is to describe an initial set of measures taken from or derived from the 2000 U.S. Census in
Langworthy, Robert H.
core
The use of Bioceramics as root-end filling materials in periradicular surgery: a literature review [PDF]
Introduction: Periradicular surgery involves the placement of a root-end filling following root-end resection, to provide an apical seal to the root canal system. Historically several materials have been used in order to achieve this seal.
Abusrewil, Sumaya M. +2 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Interfacial fracture toughness of composite concrete beams [PDF]
A test for measuring the interfacial fracture toughness of a bi-material interface, essentially for concrete overlaid pavements was developed. The measured interfacial fracture toughness of steel fibre-reinforced, roller-compacted, polymer modified ...
Karadelis, John N., Lin, Yougui
core +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source

