Results 131 to 140 of about 2,715,691 (402)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Structural Behaviour of Composite Members with Recycled Aggregate Concrete — An Overview

open access: yes, 2015
A series of investigations on structural behaviour, durability, fire-resistance and seismic performance of composite members with recycled aggregate concrete (RAC) have been carried out in the past 10 years (2005–2014).
Wengui Li   +3 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

A feasibility study on Engineered cementitious Composites mixed with coarse aggregate

open access: hybrid, 2022
Zhifu Dong   +3 more
openalex   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Influence of aggregate mineralogical composition on water resistance of aggregate–bitumen adhesion

open access: yesInternational Journal of Adhesion and Adhesives, 2015
The effects of aggregate mineralogical composition on moistures sensitivity of aggregate–bitumen bonds were investigated using four aggregate types (two limestone and two granite)and two bitumen grades (40/60 penand70/100pen). Moisture sensitivity (or water resistance) of the aggregate–bitumen bonds were characterized using retained strength obtained ...
Zhang, Jizhe   +3 more
openaire   +2 more sources

Technology strategies for low-carbon economic growth: a general equilibrium assessment [PDF]

open access: yes, 2016
This paper investigates the potential for developing countries to mitigate greenhouse gas emissions without slowing their expected economic growth. A theoretical frame- work is developed that unifies bottom-up marginal abatement cost curves and partial ...
Sue Wing, Ian, Timilsina, Govinda R.
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Kajian Eksperimen Kuat Tekan Beton Ringan Menggunakan Agregat Bambu dan Bahan Tambah Beton

open access: yesSemesta Teknika, 2016
The use bamboo as a substitute aggregate is an effort to reduce the density and static load of structural elements. This reseach focuses on the problem related to the specific gravity and compressive strength of the use of bamboo as a lightweight ...
Muhammad Riang Endarto   +1 more
doaj  

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