Results 131 to 140 of about 295,094 (360)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Experimental Study of Utilizing Recycled Fine Aggregate for the Preparation of High Ductility Cementitious Composites [PDF]

, 2020
Danying Gao, Mingyan Lv, Lin Yang, Jiyu Tang, Gang Chen, Yang Meng   +5 more
openalex   +1 more source

DESIGN AND PROPERTIES OF HOT MIXTURE POROUS ASPHALT FOR SEMI-FLEXIBLE PAVEMENT APPLICATIONS [PDF]

, 2005
Semi-flexible pavement consists of selected porous asphalt mixture filled with cementitious slurry. This new type of pavement has prospects to be designed as a high deformation resistant pavement (Setyawan et al, 2001).
Setyawan, Ary
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Physical, strength and acoustic properties of lightweight cement composite with preplaced chemically-treated crumb rubber

Case Studies in Construction Materials
The valorisation of waste tyre crumb rubber (CR) as a sustainable construction material can alleviate environmental pollution and save natural aggregate consumption. However, its use in cement composite can result in a significant loss of strength due to
Syed Nasir Shah, Salmia Beddu, Soon Poh Yap, Azma Putra, Muhammad Nur Othman, Choon Wah Yuen, Kim Hung Mo   +6 more
doaj   +1 more source

Enhancing the Thermal Properties of Cement Composites Through Substitution of the Fine Aggregate Using Metallic Material

, 2022
Jaehyun Bae, Byeong Hun Woo, Hong Gi Kim, Jae-Suk Ryou   +3 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Examining Trends in the Nonresidential Building Construction Producer Price Indexes (PPIs) [PDF]

, 2014
In 2004, the Bureau of Labor Statistics (BLS) unveiled the Producer Price Index (PPI) nonresidential building construction initiative with the publication of an index for new warehouse building construction.
Harper, Justin M
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source