Results 161 to 170 of about 299,072 (317)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Performance Testing and Evaluation of Double-Layer Pervious Concrete Based on Recycled Aggregates. [PDF]

Materials (Basel)
Jiao W, Peng Z, Ma B, Dai C, Gong B, Huang Z.   +5 more
europepmc   +1 more source

Aggregation and ecotoxicity of CeO2 nanoparticles in synthetic and natural waters with variable pH, natural organic matter concentration and ionic strength [PDF]

, 2011
De Schamphelaere, Karel, Janssen, Colin, Smagghe, Guy, Van der Meeren, Paul, Van Hoecke, Karen   +4 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Comprehensive evaluation of antibacterial activity, pH stability, and surface characterization of a mussel-inspired polymer for root perforation repair. [PDF]

Front Dent Med
Rao LN, Shetty A, Shetty V, Shetty H.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Mechanical and Dynamic Performance of a High-RAP Half-Warm Asphalt Polymeric Composite for Rapid Pavement Repair. [PDF]

Polymers (Basel)
Rodrigazo SA, Hwang IH, Cho J, You I, Kim KK, Yeon J.   +5 more
europepmc   +1 more source

Amino Acid Composition drives Peptide Aggregation: Predicting Aggregation for Improved Synthesis

Peptide aggregation is a long-standing challenge in chemical peptide synthesis, limiting its efficiency and reliability. Although data-driven methods have enhanced our understanding of many sequence-based phenomena, no comprehensive approach addresses so-called “non-random difficult couplings” (generally linked to aggregation) during solid-phase ...
Bálint Tamás, Marvin Alberts, Teodoro Laino, Nina Hartrampf   +3 more
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Investigating the influence of expanded perlite and lime mud on cement-bonded composites containing pulp sludge. [PDF]

Sci Rep
Amiandamhen SO, Mai C, van Blokland J, Daniel G, Adamopoulos S.   +4 more
europepmc   +1 more source