Results 271 to 280 of about 2,715,691 (402)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Associations between composite systemic inflammation indicators(CAR, CLR, SII, AISI, SIRI, and CALLY) and metabolic dysfunction-associated fatty liver disease (MAFLD): evidence from a two-stage study in China. [PDF]

Front Immunol
Zhao J, Zhou Q, Wang Y, Xie F, Fan J.
europepmc   +1 more source

Effect of size and loading of waste single-used plastic (SUP) aggregates on a bio-based high density polyurethane composite

Amierson C. Tilendo, K M M Uy, J Q Filipinas, K M A Marohomsalic, Jawad Khalid, Neelam Sultan   +5 more
openalex   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Sustainable cement-based mortar with shredded material recycled from end-of-life wind turbine blades. [PDF]

Sci Rep
Rucka M, Kurpińska M.
europepmc   +1 more source

CEMENTITIOUS MATRIX COMPOSITES (CMC) WITH MANUFACTURED COAL ASH AGGREGATES (MCAA)

, 2017
Chiranthan Ramesh
openalex   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Evaluation of Workability and Crack Resistance of Recycled Plastic Asphalt Mixtures. [PDF]

Polymers (Basel)
Jing H, Monticelli R, Graiff C, Bergamonti L, Romeo E, Tebaldi G.   +5 more
europepmc   +1 more source

Development Of Materials Based On Pet-Siliceous Sand Composite Aggregates

, 2018
Mohammed Touhami Gouasmi, Ahmed Soufiane Benosman, H. Taïbi   +2 more
openalex   +2 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source