HSP70 governs permeability and mechanotransduction in primary human endothelial cells
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Effects of Phosphogypsum-Recycled Aggregate Solid Waste Base on Properties of Vegetation Concrete. [PDF]
Xiao Z +5 more
europepmc +1 more source
Concrete in the low carbon era:proceedings of the International Conference held at the University of Dundee, Scotland, UK on 9 - 11 July 2012 [PDF]
Csetenyi, Laszlo J +6 more
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Study on Preparation and Properties of Phosphogypsum-Based Lightweight Thermal Insulation Materials. [PDF]
Chu Y, Jiang T, Huang H, Yi G, Huang B.
europepmc +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Sustainable Utilization of Coal Gangue in Asphalt Pavement: A Review on Design, Mechanism, and Performance. [PDF]
Jia Y +8 more
europepmc +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
Exploring the association between immune-inflammation index and carotid plaque formation: a cross-sectional study in a large Chinese health screening population. [PDF]
Sun J, Zhang X, Yang M, Yang S, Zeng H.
europepmc +1 more source

