Results 61 to 70 of about 1,654,624 (346)

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan   +5 more
wiley   +1 more source

Accounting for Aggregation Bias in Almost Ideal Demand Systems

open access: yesJournal of Agricultural and Resource Economics, 1996
This study revisits the consistent aggregation (over households) property of almost ideal demand system (AIDS) models and presents a method to explicitly account for expenditure aggregation bias when estimating the aggregate AIDS model with time-series ...
Ronald C. Mittelhammer   +2 more
doaj   +1 more source

Image Analysis and Functional Data Clustering for Random Shape Aggregate Models

open access: yesMathematics, 2020
This study presents a random shape aggregate model by establishing a functional mixture model for images of aggregate shapes. The mesoscale simulation to consider heterogeneous properties concrete is the highly cost- and time-effective method to predict ...
Jonghyun Yun   +3 more
doaj   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Local-Aggregate Modeling for Big-Data via Distributed Optimization: Applications to Neuroimaging [PDF]

open access: yes, 2015
Technological advances have led to a proliferation of structured big data that have matrix-valued covariates. We are specifically motivated to build predictive models for multi-subject neuroimaging data based on each subject's brain imaging scans.
Allen, Genevera I., Hu, Yue
core  

Parent‐to‐Child Information Disclosure in Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor   +12 more
wiley   +1 more source

FirstLight: Pluggable Optical Interconnect Technologies for Polymeric Electro-Optical Printed Circuit Boards in Data Centers [PDF]

open access: yes, 2012
The protocol data rate governing data storage devices will increase to over 12 Gb/s by 2013 thereby imposing unmanageable cost and performance burdens on future digital data storage systems.
Baghsiahi, H   +8 more
core   +1 more source

Radiotherapy Delivery in Deep Inspiration for Pediatric Patients—Final Results of the Phase II Feasibility Study TEDDI

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Introduction The TEDDI trial tested the feasibility and reproducibility of deep‐inspiration breath‐hold (DIBH) in pediatric patients referred for radiotherapy. This report presents final results, including patient‐reported outcomes (PRO) and dosimetric comparison of DIBH and free‐breathing (FB).
Daniella Elisabet Østergaard   +11 more
wiley   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura   +5 more
wiley   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd   +3 more
wiley   +1 more source

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