Results 41 to 50 of about 55,523 (310)

Production Decision Support System for Multi-product with Multiple Different Size Processors

open access: yesChemical Engineering Transactions, 2018
Aggregate planning is an operational activity with the objective of providing upfront information on quantity of material to be procured and resources to be secured. At a point of time, it might also influence both demand and supply.
Lee Pheng Chee   +2 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Diseño de un modelo de planeación agregada para las prestaciones médicas en un servicio de ginecología y obstetricia

open access: yesIngenieria Industrial, 2010
En el presente trabajo se diseña un modelo de planificación agregada dentro de la unidad de ginecología y obstetricia del Hospital Clínico Herminda Martín. Se comienza investigando los modelos que se han desarrollado para tal propósito dentro del área de
Rodrigo de la Fuente Gallegos   +1 more
doaj  

Aggregate Production Planning for Cost Optimization: A Case Study of Van’z Collection, a Small-Scale Garment Manufacturer

open access: yesSociety
This study aims to evaluate the aggregate production planning system and explore alternative aggregate strategies to improve cost efficiency in the production planning process.
Zahra Nur Afifah, Ayi Tejaningrum
doaj   +1 more source

Definition of basic and supporting parts of Alfa foils, a.s. planning system [PDF]

open access: yesActa Montanistica Slovaca, 2008
Aggregate planning cummulates into one target capacity, materials, economy and technology rules with aim to minimizesubjective approaches at the production plan designing and utilization of automatic (pseudoexpert) system for making productionplanning ...
Zuzana Marková   +2 more
doaj  

A Stochastic Programming Model for Multi-Product Aggregate Production Planning Using Valid Inequalities

open access: yesApplied Sciences, 2022
In this study, a mixed integer, linear, multi-stage, stochastic programming model is developed for multi-product aggregate production planning (APP). An approximation is used with a model that employs discrete distributions with three and four values and
José Emmanuel Gómez-Rocha   +1 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Prediction of Lifespan of Railway Ballast Aggregate According to Mechanical Properties of it

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2017
As the railway lifespan is the main criterion for selection of the aggregate for ballast and for planning the maintenance of the railroad, it is important to define the relationship between the particle load resistant characteristics and a lifetime of ...
Vaidas Ramūnas   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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