Results 101 to 110 of about 93,292 (244)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Evaluation of the mechanical characteristics of bagasse ash concrete using response surface methodology

Discover Sustainability
Assessing the mechanical properties of Sugarcane Bagasse Ash (SCBA) concrete is essential for improving its strength and durability while ensuring its viability as a sustainable building material.
Uzoma Ibe Iro, George Uwadiegwu Alaneme, Nakkeeran Ganasen, M. VishnuPriyan, Imoh Christopher Attah, Val Hyginus Udoka Eze, Bamidele Charles Olaiya, Somtochukwu Ejeabukwa   +7 more
doaj   +1 more source

Synergistic effects of GGBFS addition and oven drying on the physical and mechanical properties of fly ash-based geopolymer aggregates

Journal of Sustainable Construction Materials and Technologies
Conventional coarse aggregates, extracted from natural sources, pose environmental challenges such as habitat destruction, resource depletion, and high energy consumption.
T. Muralidhara Rao, B. Naga Malleswara Rao, Bypaneni Krishna Chaitanya, Mukkala Priyanka, Venkatesh Chava, Chereddy Sonali Sri Durga   +5 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Effect of recycled aggregates with different parent strength and fly ash on flexural strength of recycled aggregate concrete prisms

Mehran University Research Journal of Engineering and Technology
Fast consumption of conventional ingredients of concrete and waste generated due to demolishing old buildings is a multi-fold problem in the concrete industry. Hence the sustainable alternative of it is the need of the day.
Ghulam Shabir Bhatti, Bashir Ahmed Memon, Muhammad Aachar Zardari, Mahboob Oad, Riaz Bhambhro, Amjad Hussain Bhutto   +5 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Steel fibre-reinforced concrete with fully recycled coarse and partially recycled fine aggregates

Scientific Reports
The construction industry is showing an increasing interest in the integration of Recycled Aggregate (RA) into concrete as a substitute for natural coarse aggregate, whether in full or in part, with the aim of reducing dependence on virgin aggregate ...
M. Saravanan, R. Nirmala
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source