Results 41 to 50 of about 1,171,691 (282)

Review on Approaches of Federated Modeling in Anomaly-Based Intrusion Detection for IoT Devices

IEEE Access
The novelty of Federated Learning (FL) has emerged as a promising alternative to centralized machine learning systems in the context of anomaly-based intrusion detection systems (AIDS) deployed on Internet of Things (IoT) devices.
Umar Audi Isma'ila, Kamaluddeen Usman Danyaro, Aminu Aminu Muazu, Umar Danjuma Maiwada   +3 more
doaj   +1 more source

O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease. [PDF]

, 2015
Several aggregation-prone proteins associated with neurodegenerative diseases can be modified by O-linked N-acetyl-glucosamine (O-GlcNAc) in vivo. One of these proteins, α-synuclein, is a toxic aggregating protein associated with synucleinopathies ...
Ambroso, Mark R, Arnold, Don B, Langen, Ralf, Lewis, Yuka E, Lin, Yu Hsuan, Marotta, Nicholas P, Pratt, Matthew R, Roth, Maxwell T, Zaro, Balyn W   +8 more
core   +2 more sources

Research on Spatial Data Aggregation Based on Aggregation Degree Function [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Restricted by the development level of hardware and software technology, computers cannot load massive data at one time, coupled with the fact that the three-dimensional linear scene is characterized by complicated lines, irregular shapes of features and
Z. Zeng, L. Huo, W. Zhu, P. Bao, Y. Li, M. Zhang   +5 more
doaj   +1 more source

Axiomatizations of signed discrete Choquet integrals [PDF]

, 2010
We study the so-called signed discrete Choquet integral (also called non-monotonic discrete Choquet integral) regarded as the Lov\'asz extension of a pseudo-Boolean function which vanishes at the origin.
Cardin, Marta, Couceiro, Miguel, Giove, Silvio, Marichal, Jean-Luc   +3 more
core   +4 more sources

A Quality Improvement Initiative to Standardize Pneumocystis jirovecii Pneumonia Prophylaxis in Pediatric Patients With Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

Sickle Cell Disease Is an Inherent Risk for Asthma in a Sibling Comparison Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Sickle cell disease (SCD) and asthma share a complex relationship. Although estimates vary, asthma prevalence in children with SCD is believed to be comparable to or higher than the general population. Determining whether SCD confers an increased risk for asthma remains challenging due to overlapping symptoms and the ...
Suhei C. Zuleta De Bernardis, Okeleji Olayinka, Mariam Z. Quraishi, Lakshmi V. Srivaths, Deborah L. Brown, Neethu M. Menon, Ricardo A. Mosquera, Ashwin P. Patel, James M. Stark, Aravind Yadav   +9 more
wiley   +1 more source

p53 amyloid aggregation in cancer: function, mechanism, and therapy

Experimental Hematology & Oncology, 2022
Similar to neurodegenerative diseases, the concept that tumors are prion like diseases has been proposed in recent years. p53, the most well-known tumor suppressor, has been extensively studied for its expression, mutation, and function in various tumors.
Jingzhi Li, Ming Guo, Lin Chen, Zhuchu Chen, Ying Fu, Yongheng Chen   +5 more
doaj   +1 more source

Aggregation is a Context-Dependent Constraint on Protein Evolution

Frontiers in Molecular Biosciences, 2021
Solubility is a requirement for many cellular processes. Loss of solubility and aggregation can lead to the partial or complete abrogation of protein function. Thus, understanding the relationship between protein evolution and aggregation is an important
Michele Monti, Michele Monti, Alexandros Armaos, Alexandros Armaos, Marco Fantini, Annalisa Pastore, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia   +9 more
doaj   +1 more source

Pazopanib Combined With Vincristine and Irinotecan in Relapsed Wilms Tumor: Encouraging Outcomes in a Heavily Pretreated Pediatric Cohort

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While Wilms tumor (WT) typically has a favorable prognosis, relapsed cases—especially those with high‐risk histology—remain therapeutically challenging after intensive frontline therapy. The combination of vincristine and irinotecan has demonstrated activity in pediatric solid tumors, and pazopanib, a multi‐targeted tyrosine kinase ...
Maria Debora De Pasquale, Alessandro Crocoli, Giuseppe Maria Milano, Pierluigi Di Paolo, Francesca Diomedi Camassei, Ida Russo, Annalisa Serra   +6 more
wiley   +1 more source

Weibull-type limiting distribution for replicative systems

, 2011
The Weibull function is widely used to describe skew distributions observed in nature. However, the origin of this ubiquity is not always obvious to explain.
Jean-Yves Fortin, Junghyo Jo, M. Y. Choi, O. Kallenberg, T. E. Harris, W. Weibull   +5 more
core   +1 more source