Results 101 to 110 of about 1,560,028 (331)

Numerical heat performance of TiO2/Glycerin under nanoparticles aggregation and nonlinear radiative heat flux in dilating/squeezing channel

Case Studies in Thermal Engineering, 2023
Applications: Newly developed fluids termed as “Nanofluids” and their study in dilating/squeezing channel cannot be disregarded. Such flows under various physical constraints are important for purification purposes and other industrial applications ...
Adnan, Khalid Abdulkhaliq M Alharbi, Mutasem Z. Bani-Fwaz, Sayed M. Eldin, Mansour F. Yassen   +4 more
doaj  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Mesoscale Near-Surface Wind Speed Variability Mapping with Synthetic Aperture Radar

Sensors, 2008
Operationally-significant wind speed variability is often observed within synthetic aperture radar-derived wind speed (SDWS) images of the sea surface.
George Young, Nathaniel Winstead, Todd Sikora   +2 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Application of single-molecule analysis to singularity phenomenon of cells

Biophysics and Physicobiology
Single-molecule imaging in living cells is an effective tool for elucidating the mechanisms of cellular phenomena at the molecular level. However, the analysis was not designed for throughput and requires high expertise, preventing it from reaching large
Michio Hiroshima, Hiroko Bannai, Gen Matsumoto, Masahiro Ueda   +3 more
doaj   +1 more source

Dynamics of Aggregation in Systems of Self-Propelled Rods

Entropy
We highlight camphene–camphor–polypropylene plastic as a useful material for self-propelled objects that show aggregation while floating on a water surface.
Richard J. G. Löffler, Jerzy Gorecki
doaj   +1 more source

Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases

European Journal of Histochemistry, 2013
Formation, aggregation and transmission of abnormal proteins are common features in neurodegenerative disorders including Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, and Huntington’s disease. The mechanisms underlying protein
G. Natale, E. Pompili, F. Biagioni, S. Paparelli, P. Lenzi, F. Fornai   +5 more
doaj   +1 more source

On a class of reaction-diffusion equations with aggregation [PDF]

arXiv, 2019
In this paper, global-in-time existence and blow up results are shown for a reaction-diffusion equation appearing in the theory of aggregation phenomena (including chemotaxis). Properties of the corresponding steady-state problem are also presented. Moreover, the stability around constant equilibria and the non-existence of non-constant solutions are ...
arxiv  

Two-phase densification of cohesive granular aggregates [PDF]

, 2001
When poured into a container, cohesive granular materials form low-density, open granular aggregates. If pressed upon with a ram, these aggregates densify by particle rearrangement. Here we introduce experimental evidence to the effect that particle rearrangement is a spatially heterogeneous phenomenon, which occurs in the form of a phase ...
arxiv   +1 more source