Results 101 to 110 of about 1,702,102 (343)

Boltzmann-type models with uncertain binary interactions

, 2017
In this paper we study binary interaction schemes with uncertain parameters for a general class of Boltzmann-type equations with applications in classical gas and aggregation dynamics.
Tosin, Andrea, Zanella, Mattia
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Application of single-molecule analysis to singularity phenomenon of cells

Biophysics and Physicobiology
Single-molecule imaging in living cells is an effective tool for elucidating the mechanisms of cellular phenomena at the molecular level. However, the analysis was not designed for throughput and requires high expertise, preventing it from reaching large
Michio Hiroshima, Hiroko Bannai, Gen Matsumoto, Masahiro Ueda   +3 more
doaj   +1 more source

Synthesis and Characterization of Multilayer 3D Chiral Polymers with Enhanced Optical Properties

Molecules
This study reports the synthesis of novel multilayer 3D chiral polymers using 2,2′-(2,7-Naphthalenediyl)bis[4,4,5,5-tetramethyl-1,3,2-dioxaborolane] and 1,8-dibronaphthalene along with its derivatives as key precursors. Comprehensive characterization was
Sai Zhang, Xiaobei Jin, Daixiang Chen, Qingzheng Xu, Tao Wang, Xiuyuan Qin, Jialing Mao, Yue Zhang, Shenghu Yan, Guigen Li   +9 more
doaj   +1 more source

Aggregation of magnetic holes in a rotating magnetic field

, 2008
We have experimentally investigated field induced aggregation of nonmagnetic particles confined in a magnetic fluid layer when rotating magnetic fields were applied.
Geir Helgesen, Jozef Černák, T. Vicsek
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Mesoscale Near-Surface Wind Speed Variability Mapping with Synthetic Aperture Radar

Sensors, 2008
Operationally-significant wind speed variability is often observed within synthetic aperture radar-derived wind speed (SDWS) images of the sea surface.
George Young, Nathaniel Winstead, Todd Sikora   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Histochemical approaches to assess cell-to-cell transmission of misfolded proteins in neurodegenerative diseases

European Journal of Histochemistry, 2013
Formation, aggregation and transmission of abnormal proteins are common features in neurodegenerative disorders including Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, and Huntington’s disease. The mechanisms underlying protein
G. Natale, E. Pompili, F. Biagioni, S. Paparelli, P. Lenzi, F. Fornai   +5 more
doaj   +1 more source

(WP 2015-03) Lawson on Veblen on Social Ontology [PDF]

, 2015
This paper discusses Lawson’s use of Veblen’s concept of ‘neoclassical economics’ and argument that the category of neoclassical economics should be jettisoned on the grounds that it obfuscates effective critique of mainstream economics.
Davis, John B.
core   +1 more source