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Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Autoregressive models for session-based recommendations using set expansion. [PDF]

PeerJ Comput Sci
Yu T, Zhou X, Deng X.
europepmc   +1 more source

Deep learning for fine-grained molecular-based colorectal cancer classification. [PDF]

Transl Cancer Res
Bian J, Li Y, Dang Y, Chen Y.
europepmc   +1 more source

System Mapping of Farm-to-School Partnerships to Enhance Student Access to Healthy, Local Foods. [PDF]

Int J Environ Res Public Health
Guillen M, Soule KE.
europepmc   +1 more source

Privacy-preserving federated unsupervised domain adaptation with application to age prediction from DNA methylation data. [PDF]

Bioinformatics
Baykara CA, Ünal AB, Pfeifer N, Akgün M.   +3 more
europepmc   +1 more source

Enrichment of Germline Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Pathogenic Variants in Patients With Solid Tumors: Evidence for Increased Cancer Risk. [PDF]

Pediatr Pulmonol
Shugg T, Gallaway KA, Powell N, Skaar TC, Bray SM, Stout LA, Colwell A, Brown CD, Slaven JE, Tillman EM.   +9 more
europepmc   +1 more source

Optimal two-stage arbitraging and scheduling strategy for distributed energy resource aggregators. [PDF]

Heliyon
Xie P, Liu M, Chen C, Tang W, Wang H.
europepmc   +1 more source

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Data-Driven Risk-Adjusted Robust Energy Management for Microgrids Integrating Demand Response Aggregator and Renewable Energies

IEEE Transactions on Smart Grid, 2023
Microgrids, integrating user-side demand response and zero marginal cost renewable energies, are potential components for future smart grids to reduce carbon emissions and improve power system resilience.
Peng Li
exaly   +2 more sources