Results 71 to 80 of about 1,108,330 (257)

The Independent and Combined Roles of Attentional and Interpretative Biases in Antisocial Behavior, Trait Aggression and Aggressive Responses Under Provocation

open access: yes
Data Availability Statement: The data that support the findings will be made openly available at the University of Reading data archive.At head of title: Brief report.Aggressive behavior has been linked to biases in social information processing ...
Kumari, Veena   +5 more
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Prosocial and aggressive related behaviors: the role of positivity and social support during the pandemic

open access: yes, 2022
The following work was aimed to explore whether positivity and family’ and friends ‘support influence prosocial-related (i.e., actions and feelings; Luengo Kanacri et al., 2021) and aggressive-related behaviors during the COVID-19 pandemic in Italy ...
Concetta Pastorelli   +2 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Role of moral beliefs in aggression: an investigation across two cultures [PDF]

open access: yes
The overarching aim of this thesis was to contribute to the understanding of specific moral-cognitive processes and mechanisms and their association with aggressive behaviour across age groups and across two cultures.
Amjad, Naumana
core  

Television and aggressive behaviour 1979-1981

open access: yes, 2007
Dutch contribution to a cross-national survey to investigate the effect of television violence viewing on the behaviour of children. This Dutch survey also investigated the effects of tv- shows on pro-social behaviour.
Wiegman, O., Kutschreuter, M., Baarda, B., Rijksuniversiteit Utrecht * Utrecht, Fac. sociale wetenschappen, vakgroep kinderstudies (primary investigator)
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

The psychosocial factors influencing aggressive driving behaviour [PDF]

open access: yes, 2011
Many drivers in highly motorised countries believe that aggressive driving is increasing. While the prevalence of the behaviour is difficult to reliably identify, the consequences of on-road aggression can be severe, with extreme cases resulting in ...
O'Brien, Sharon Rosemary
core  

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