Results 131 to 140 of about 623,479 (312)

A Principled Framework for Mendelian Randomization in Oral Health Research

Journal of Periodontal Research, EarlyView.
This methodological article provides a clear and accessible overview of Mendelian randomization for oral health researchers, emphasizing the core assumptions needed for credible causal inference. Focusing on applications in oral health, particularly periodontitis, it highlights both the strengths and limitations of the study design in order to support ...
Nasir Z. Bashir, Mario Romandini, Moritz Kebschull, Konstantinos K. Tsilidis, Dominique S. Michaud, Stephen Burgess   +5 more
wiley   +1 more source

Clinical application of genetics to guide prevention and treatment of oral diseases [PDF]

, 2014
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/107353/1/cge12396 ...
Kornman, K.S., Polverini, P.J.
core   +1 more source

Assessment of microRNA-146a in generalized aggressive periodontitis and its association with disease severity.

Journal of Periodontal Research, 2018
BACKGROUND AND OBJECTIVE MicroRNA-146a (miR-146a) is a small noncoding RNA that plays a critical role in the negative regulation of the innate immune response, and the dysregulation of miR-146a has been associated with several inflammatory disorders.
S. Ghotloo, H. Motedayyen, D. Amani, M. Saffari, M. Sattari   +4 more
semanticscholar   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

The effect of smoking on myeloid-related protein-8 and myeloid-related protein-14

Brazilian Oral Research, 2016
The aim of this study was to determine the myeloid-related protein-8 and myeloid-related protein-14 levels in the gingival crevicular fluid of smoker patients with generalized aggressive periodontitis (SAgP), smoker patients with chronic periodontitis ...
Abdullah Seckin ERTUGRUL, Hacer SAHİN
doaj   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Toll-like receptor–4 gene polymorphisms in Javanese aggressive and chronic periodontitis patients

Dental Journal, 2015
Background: Tool-like receptor-4 (TLR4) gene polymorphisms affect the ability of the host in response to pathogenic bacteria, and can also be associated with the severity of periodontitis.
Chiquita Prahasanti
doaj   +1 more source

Periodontal status among adolescents in Georgia. A pathfinder study [PDF]

, 2013
Objectives. The aim of the present pathfinder study was to screen and map the periodontal status of Georgian population in accordance with the guidelines of the World Health Organization for population based surveys. Methods.
Eli E. Machtei, Leon Bilder, Liran Levin, Manana Kalandadze, Nino Tsintsadze, Vladimer Margvelashvili   +5 more
core   +1 more source

Role of Keratinized Mucosa on the Risk of Peri‐Implant Diseases and Soft Tissue Dehiscence in the Posterior Mandible—A 20‐Year Prospective Cohort Study

Journal of Periodontal Research, EarlyView.
The application of an FGG at tissue level implants in the posterior mandible had a positive effect on clinical and radiographic outcomes and peri‐implant conditions after 20 years of function. ABSTRACT Aim To evaluate the 20‐year outcomes of tissue‐level implants placed in the posterior mandible, comparing implants surrounded by keratinized tissue (KT)
Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Mario Romandini, Anton Sculean, Giovanni E. Salvi, Mario Roccuzzo   +6 more
wiley   +1 more source

FREQUENCY OF TLR-2, 4, 9 AND CD14 POLYMORPHISMS IN AGGRESSIVE PERIODONTITIS POPULATION IN AFRICAN-AMERICANS [PDF]

, 2009
Aim: The aim of this study is to determine the frequency of single nucleotide polymorphisms (SNPs) in various pattern recognition receptor (PRR) genes, including Toll like receptors (TLR) -2, -4, -9, and CD14 in chronic (CP), localized (LAP) and ...
Chou, Melanie
core   +1 more source