Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
TINJAUAN YURIDIS ASAS ITIKAD BAIK DALAM TRANSAKSI ELEKTRONIK SEBAGAI PERLINDUNGAN HUKUM TERHADAP KONSUMEN [PDF]
The principle of good faith is very important in electronic buying and selling transactions as an effort to protect consumers. This principle is regulated in Article 1338 paragraph (3) of the Civil Code and is considered fundamental in agreements ...
Islamiyah, Erina Nur
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Journal of Education, Health and Sport, 2015 Mazur Zuzanna, Organista Natalia. Poziom agresywności kobiet uprawiających sporty rodzajowo męskie i kobiece = The level of social aggressiveness in women practising male or female sports. Journal of Education, Health and Sport. 2015;5(5):151-164.
Zuzanna Mazur, Natalia Organista
doaj
VALIDACIÓN DE LA VERSIÓN MEXICANA DEL INVENTARIO DE EXPRESIÓN DE IRA ESTADO-RASGO (STAXI-2) [PDF]
Acta Colombiana de Psicología, 2010 The aim of the study was to determine the psychometric properties of the Mexican version of the State-Trait Anger Expression Inventory (STAXI-2; Miguel-Tobal, Casado, Can-Vindel & Spielberger, 2001). Participants were 865 people, with ages between 12 and
Oliva Mendoza, Félix Jesús +2 more
doaj
Aggressive behavior in humans: Genes and pathways identified through association studies [PDF]
, 2016 Noèlia Fernàndez‐Castillo +1 more
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
, 2016 Contains fulltext : 157515.pdf (Publisher’s version ) (Open Access)
Didden, H.C.M. +9 more
openaire +2 more sources
Prognostic Factors in Patients With Aggressive Non-Hodgkin's Lymphoma Treated by Front-Line Autotransplantation After Complete Remission: A Cohort Study by the Groupe d'Etude des Lymphomes de l'Adulte [PDF]
, 2004 Nicolas Mounier +13 more
openalex +1 more source
IDDF2020-ABS-0147 Development of a validated nomogram to predict aggressive Crohn’s disease: a retrospective cohort study [PDF]
, 2020 Jiayin Yao +3 more
openalex +1 more source