Results 121 to 130 of about 384,572 (335)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pacifism and Emotional Arousal

open access: yes, 1991
Excerpt: At the age of eighteen, American youths must make an ideological decision about war. Although most probably perceive selective service registration as little more than a rite of passage, others struggle with the ethics of military service and ...
Benson, Stephen L.   +4 more
core  

Oxidative stress adaptation in aggressive prostate cancer may be counteracted by the reduction of glutathione reductase [PDF]

open access: gold, 2012
Mariana Freitas   +5 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

El imaginario, narcisismo y agresividad en psicoanálisis: del joven Lacan a la violencia urbana // Imaginary, narcissism and aggressivness in psychoanalysis: since young Lacan until urban violence

open access: yesAffectio Societatis, 2011
El presente artículo pretende establecer, a partir de la pregunta por la constitución subjetiva, un recorrido teórico por algunas de las grandes problemáticas en torno a lo imaginario, el narcisismo y la agresividad, tal y como se desprenden de algunos ...
Patricio Rojas Navarro
doaj  

Is primary thoracic ewing sarcoma aggressive than others? seventeenyears' experience [PDF]

open access: diamond, 2021
Seray Hazer   +7 more
openalex   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Aggressiveness traits, fitness and insights in their genetic basis in Magnaporthe oryzae [PDF]

open access: yes, 2014
Partial resistance is often presented as an alternative to the frequent failure of complete and specific resistance of plants to pathogens. Partial resistance is presumed to be non-specific and multigenic.
Adreit, Henri   +7 more
core  

Home - About - Disclaimer - Privacy