Results 131 to 140 of about 384,572 (335)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Libido, aggression and aggressiveness

open access: yes, 1993
Referat, predstavljen na prvem Vzhodnoevropskem psihoanalitičnem seminarju,na Dunaju, (april 1993) predstavlja pregled zadnjih sprememb v psihoanalitičnem konceptu agresije. Zavzema se za doslednejšo rabo pojmov agresije in agresivnosti - prvega za destruktivne pojave in oblike, drugega za označevanje gonskih silnic, agresivnih teženj, ki se kažejo kot
openaire   +2 more sources

Aggressive flossing [PDF]

open access: yesBritish Dental Journal, 2013
I, Hunt, S, Ryatt
openaire   +2 more sources

Neuroimaging Assessment of Aggressive Pituitary Adenomas

open access: diamond, 2021
Khalimova Zamira Yusupovna   +1 more
openalex   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Death Drive and Critical Theory

open access: yesCritical Hermeneutics
Much has been said about death drive in Critical Theory. This concept was mainly read as an aggressive and/or destructive drive. As a consequence, there are two ways of finding death drive in critical theories: the classic mode represented by Adorno ...
Inara Luisa Marin
doaj   +1 more source

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