Results 171 to 180 of about 231,360 (291)

Patterns of spinal motion, kinematic spaces and the land‐to‐sea transition in carnivorans

open access: yesThe Anatomical Record, EarlyView.
Using 3D reconstructions, we quantify intervertebral joint mobility to investigate how cervical, thoracic, and lumbar vertebral regions evolved distinct kinematic roles in pinnipeds. The findings reveal lineage‐specific adaptations for swimming and highlight the functional significance of vertebral joint flexibility in ecological transitions.
Juan Miguel Esteban   +3 more
wiley   +1 more source

Loss of Tripartite Motif–Containing Protein 21 and UVB‐Induced Systemic Inflammation by Regulating DNA‐Sensing Pathways

open access: yesArthritis &Rheumatology, EarlyView.
Objective Patients with systemic lupus erythematosus (SLE) experience photosensitivity, with exposure to UVB light driving lupus flares and triggering symptoms like joint pain, fatigue, and cutaneous lesions. Although the mechanism(s) linking UVB exposure to systemic effects are unclear, type I interferons (IFNs) are known to play a role.
Gantsetseg Tumurkhuu   +17 more
wiley   +1 more source

Wearable exoskeleton robot control using radial basis function‐based fixed‐time terminal sliding mode with prescribed performance

open access: yesAsian Journal of Control, EarlyView.
Abstract This paper tackles the problem of robust and accurate fixed‐time tracking in human–robot interaction and deals with uncertainties. This work introduces a control approach for a wearable exoskeleton designed specifically for rehabilitation tasks.
Mahmoud Abdallah   +4 more
wiley   +1 more source

Evaluation of the Medicines and Healthcare products Regulatory Agency's introduction of a risk‐proportionate approach for clinical trials: An analysis of 4617 applications assessed between September 2023 and August 2024

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims The Medicines and Healthcare products Regulatory Agency (MHRA) introduced a risk‐proportionate approach to assess clinical trial applications for authorisation in August 2023. This study evaluates the impact of this approach on the timelines for reviewing proposals.
Andrea Manfrin   +6 more
wiley   +1 more source

Sustaining the teaching profession: Innovating the ‘golden thread’ in university‐led teacher education

open access: yesBritish Educational Research Journal, EarlyView.
Abstract This paper examines the implications of England's ‘golden thread’ policy framework for teacher education, which describes a state‐mandated, linear model of professional learning from initial teacher training and education through to continuing professional development.
Amanda Nuttall   +3 more
wiley   +1 more source

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