Results 331 to 340 of about 1,200,697 (382)

Designer Solid Self‐Emulsifying Nanovaccines Enable Dual Modulation of Dendritic Cells and T Cells for Potent Antitumor Immunity

Advanced Science, EarlyView.
A solid self‐emulsifying (SSE) platform is loaded with peptide antigens and CpG to form the SSE vaccine. An ApoE‐enriched corona promotes dendritic cell internalization, enabling antigen presentation and T cell activation. Squalene from the SSE also sensitizes T cells by promoting lipid raft formation.
Xueying Shen, Shiqi Fan, Jia He, Lanqing Luo, Junyao Li, Chengcheng Wu, Kairu Yang, Xiaojun Xia, Rui Kuai   +8 more
wiley   +1 more source

Single-molecule methods for characterizing receptor dimers reveal metastable opioid receptor homodimers that induce functional modulation. [PDF]

Nat Commun
Zhou P, Tsunoyama TA, Kasai RS, Hirosawa KM, Kalay Z, Aladag A, Fujiwara TK, Yokoyama T, Sakamoto M, Kise R, Yanagawa M, Inoue A, Pigolotti S, Kusumi A.   +13 more
europepmc   +1 more source

GLP-1 receptor agonists and cancer: current clinical evidence and translational opportunities for preclinical research. [PDF]

J Clin Invest
Valencia-Rincón E, Rai R, Chandra V, Wellberg EA.   +3 more
europepmc   +1 more source

Characterisation of an unusual nicotinic acetylcholine receptor subtype preferentially sensitive to biogenic amines. [PDF]

Commun Biol
Mitchell EL, Armstrong EB, Viscarra F, Bermudez I, Biggin PC, Goodchild JA, Jones AK.   +6 more
europepmc   +1 more source

Targeting disrupted networks in schizophrenia: Can muscarinic drugs make a fundamental difference? [PDF]

J Psychopharmacol
Pratt JA, Morris BJ.
europepmc   +1 more source

Does Every Person with Asthma Need an Inhaled Corticosteroid? [PDF]

Ann Am Thorac Soc
Farber HJ.
europepmc   +1 more source

cGAS-STING signaling in the tumor microenvironment induces myeloid cell activation and favors T cell-mediated antitumor immunity. [PDF]

Cancer Biol Ther
Ren M, Ai ZE, Zhang Y, Shi L, Liu Y, Liu H, Shen H, Yao X, Yan Z.   +8 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Daily Oral GLP-1 Receptor Agonist Orforglipron for Adults with Obesity.

New England Journal of Medicine, 2023
BACKGROUND Obesity is a major risk factor for many leading causes of illness and death worldwide. Data are needed regarding the efficacy and safety of the nonpeptide glucagon-like peptide-1 (GLP-1) receptor agonist orforglipron as a once-daily oral ...
S. Wharton, T. Blevins, Lisa E. Connery, J. Rosenstock, Sohini Raha, Rong Liu, Xiaosu Ma, K. Mather, A. Haupt, D. Robins, E. Pratt, C. Kazda, Manige Konig   +12 more
semanticscholar   +1 more source

An orally available non-nucleotide STING agonist with antitumor activity

Science, 2020
Targeting STING for cancer therapy Activation of the STING (stimulator of interferon genes) protein by cyclic dinucleotide metabolites plays a critical role in antitumor immunity.
B. Pan, Samanthi A. Perera, J. Piesvaux, J. Presland, Gottfried K. Schroeder, J. Cumming, B. Trotter, M. Altman, A. Buevich, B. Cash, S. Cemerski, Wonsuk Chang, Yiping Chen, P. Dandliker, Guo Feng, Andrew M Haidle, T. Henderson, James P. Jewell, I. Kariv, Ian Knemeyer, J. Kopinja, Brian M. Lacey, J. Laskey, C. Lesburg, Rui Liang, B. Long, Min Lu, Yanhong Ma, E. Minnihan, Greg O'Donnell, Ryan Otte, Laura Price, L. Rakhilina, B. Sauvagnat, Sharad K Sharma, S. Tyagarajan, Hyun Woo, D. Wyss, Serena Xu, D. J. Bennett, G. Addona   +40 more
semanticscholar   +1 more source