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Body and organ mass in agouti and non-agouti deer mice (Peromyscus maniculatus)
Comparative Biochemistry and Physiology Part A, Molecular & Integrative Physiology, 2001Body, adrenal, brain, heart, liver, kidney, spleen and testis masses were determined for agouti and non-agouti deer mice (Peromyscus maniculatus gracilis) of both sexes. Body mass was highest for non-agouti females and lowest for agouti females; and sex differences in body mass were significant for agouti, but not non-agouti, deer mice.
exaly +3 more sources
Inverse agonist activity of agouti and agouti-related protein
Peptides, 2003Agouti and agouti-related protein (AgRP) are endogenous antagonists of the melanocortin receptors (MCxR). Previous data showed that recombinant full-length agouti and a synthetic fragment of AgRP, AgRP (83-132), are inverse agonists at the MC1R and MC4R, respectively.
Biao-Xin, Chai +9 more
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Structures of the Agouti Signaling Protein
Journal of Molecular Biology, 2005Expression of the agouti signaling protein (ASIP) during hair growth produces the red/yellow pigment pheomelanin. ASIP, and its neuropeptide homolog the agouti-related protein (AgRP) involved in energy balance, are novel, paracrine signaling molecules that act as inverse agonists at distinct subsets of melanocortin receptors. Ubiquitous ASIP expression
Joseph C, McNulty +7 more
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Placenta, 2002
Placentae of three hystricimorph rodents--capybara, agouti and paca--were examined by conventional histology, immunohistochemistry for cytokeratin and vimentin, and TUNEL staining. The placentae were divided into lobules of labyrinthine syncytium separated by interlobular and marginal trophoblast.
Miglino, M. +3 more
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Placentae of three hystricimorph rodents--capybara, agouti and paca--were examined by conventional histology, immunohistochemistry for cytokeratin and vimentin, and TUNEL staining. The placentae were divided into lobules of labyrinthine syncytium separated by interlobular and marginal trophoblast.
Miglino, M. +3 more
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Molecular Interaction of Agouti Protein and Agouti-Related Protein with Human Melanocortin Receptors
Biochemistry, 1998Agouti protein and the Agouti-related protein (AGRP) are antagonists of the melanocortin-3 receptor and melanocortin-4 receptor. Both proteins contain 10 cysteines in the C-terminal domain arranged in five disulfide bonds. One possible arrangement of the disulfide bonds predicts an octapeptide loop, and the chemical properties of four residues within ...
M R, Tota +6 more
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Agouti‐Related Proteins (AGRPs) and Agouti‐Signaling Peptide (ASIP) in Fish and Chicken
Annals of the New York Academy of Sciences, 2005Abstract: We performed an intensive search on sequence databases to identify orthologues of ASIP and AGRP peptides in a number of different species, revealing a number of genomic fragments coding for the C‐terminal part of agouti‐related motifs, different from annotated peptide sequences, including one fragment from chicken, two from zebrafish, two ...
Janis, Klovins, Helgi B, Schiöth
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Helminth parasites of the Trinidad Agouti, Dasyprocta Agouti.
1950DuPorte, E. (Supervisor)
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The agouti gene: turned on to yellow
Trends in Genetics, 1994The agouti locus was first identified as a result of its effects on the type and temporal deposition of coat color pigments in mammals. Many mutations at the murine agouti locus have now been found, some of which not only affect coat color, but also interfere with diverse biological processes leading to diabetes, obesity, tumor susceptibility and ...
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