Results 21 to 30 of about 7,983,895 (297)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Pastures, crops, and inequality: Questioning the inverse relationship between farm size and productivity in Colombia

Mundo Agrario, 2020
The Colombian countryside has long been dominated by grass and inequality. Economic theory (i.e., the inverse relationship between farm size and productivity) holds that the monopolization of land by ranchers is irrational since farming is more ...
Shawn Van Ausdal
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Los orígenes del capitalismo comercial, la expansión colonial y la historia como teoría. Una entrevistaa Jairus Banaji

Historia Crítica, 2023
Objective/Context: In this interview, I propose a journey through the intellectual trajectory of Jairus Banaji. It focuses on different aspects comprising the study of the history of capitalism from a Marxist perspective, delving into the expansion of ...
Juan Vicente Iborra Mallent
doaj   +1 more source

Agrarian history in Uruguay: From the “agrarian question” to the present

Historia Agraria Revista de agricultura e historia rural, 2020
This paper analyses Uruguayan historiography on agrarian and rural themes from 1970 to the present. It is not a directory of authors or contributions, nor does it present bibliometric indicators to describe the agrarian historiography of Uruguay. The main point of this article is that the rise and fall of Uruguayan rural historiography depict the life ...
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Direitos de propriedade em terras rebeldes: as sesmarias dos Palmares de Pernambuco, 1678-1775

Ler História, 2017
This article analyzes the dynamics of land granting (sesmarias) in Portuguese America by focusing on a specific case study: the lands belonging to the former and defeated communities of the Palmares maroons, in the captaincy of Pernambuco.
Felipe Aguiar Damasceno
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

PERUBAHAN STRUKTUR AGRARIA DI HULU DAS CIDANAU KABUPATEN SERANG PROVINSI BANTEN

Jurnal Agrisep, 2011
The course of peasant’s history in Indonesia was colored by superlocal power domination in the form of which vary from time to time depending on the political interest and economical regime of the ruling class.
Hidayat Hidayat
doaj   +1 more source