Results 161 to 170 of about 8,082,541 (336)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Agreement testing of AMSTAR-PF, a tool for quality appraisal of systematic reviews of prognostic factor studies. [PDF]
Henry ML +28 more
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Reliability of Gemini 2.5 Pro, ChatGPT 4.1, DeepSeek V3, and Claude Opus 4 in generating standardized CMR protocols. [PDF]
Licu RA +11 more
europepmc +1 more source
LEGAL PROTECTION FOR PARTIES THAT MAKE BINDING AGREEMENTS FOR THE SALE AND PURCHASE OF LAND THAT HAS NOT BEEN CERTIFIED IN THE RESOLVING LAND PARCELS PROCESS [PDF]
Heriyanti Heriyanti
openalex +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

