Results 231 to 240 of about 7,942,911 (287)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Agreement between swept-source OCT-based and Scheimpflug-based optical biometers in myopic children. [PDF]

Int J Ophthalmol
Qin YY, Zhang ZT, Xing SW, Lin SY, Chen BZ, Liu LP, Ni Y.   +6 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Strengthening Primary Health Care in Europe: A Delphi study towards accessibility, equity and continuity of care. [PDF]

Eur J Gen Pract
Gefaell Larrondo I, Ares-Blanco S, Guisado-Clavero M, Mira JJ, Pérez Esteve C, Adler L, Bensemmane S, Kostić M, Mortsiefer A, Petrazzuoli F, Gómez-Bravo R, Astier-Peña P.   +11 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Assessing the Accuracy of Symptoms and Adverse Events Reporting for Lung Cancer Treatment in the Danish National Patient Registry. [PDF]

Clin Epidemiol
Dybdahl KL, Bak JK, Ekroll E, Søreid MK, Hansen DF, Szejniuk WM, Bøgsted M, Vesteghem C.   +7 more
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Mental Health Professionals' Attitudes Towards the Network Theory of Mental Disorders. [PDF]

Clin Psychol Eur
Schumacher L, Kriston L.
europepmc   +1 more source

Comparison of human-AI agreement in ASA scoring by gender and duration of clinical experience: a real-world study. [PDF]

BMC Med Inform Decis Mak
Çatak T, Aksu A, Saltalı AÖ, Berilgen B.   +3 more
europepmc   +1 more source

Implementing log file-based patient-specific QA for VMAT plans: A comparative study of MobiusFX and measurement-based approaches. [PDF]

J Appl Clin Med Phys
Sawapabmongkon T, Changkaew P, Puttanawarut C, Tangboonduangjit P, Khachonkham S.   +4 more
europepmc   +1 more source