Results 81 to 90 of about 3,825,049 (259)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Community Impact Evaluation. Telling a stronger story

open access: yesCommunity Psychology in Global Perspective, 2019
This paper presents the Community Impact model, which provides a systematic evaluation of a programme or intervention and, consistent with Community Psychology methodologies, proposes new perspectives in selecting strategic tools to support systems ...
Patrizia Meringolo   +2 more
doaj  

Tier-based strict locality and the typology of agreement

open access: yesJournal of Language Modelling
This paper presents a subregular analysis of syntactic agreement patterns modeled using command strings over Minimalist Grammar (MG) dependency trees (Graf and Shafiei 2019), incorporating a novel MG treatment of agreement.
Kenneth Hanson
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Agreement in Turkish relative clauses

open access: yes, 2022
In this chapter I propose an explanation for why oblique objects in Turkishpattern with canonical, accusative-marked objects in relativization out of activeconstructions, but with subjects in relativization out of passive constructions.
Gracanın Yüksek, Martına
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Staccato: Segmentation Agreement Calculator according to Thomann [PDF]

open access: yes, 2011
Lücking A, Ptock S, Bergmann K. Staccato: Segmentation Agreement Calculator according to Thomann. In: Efthimiou E, Kouroupetroglou G, eds. Proceedings of the 9th International Gesture Workshop: Gestures in Embodied Communication and Human-Computer ...
Ptock, Sebastian   +4 more
core  

Repeatability and agreement of a new anterior segment optical coherence tomography with standard devices in normal, keratoconus, and post-refractive eyes

open access: yesIndian Journal of Ophthalmology
Purpose: To assess repeatability and agreement of Eyestar 900 (Haag-Streit, Köniz, Switzerland) with Pentacam AXL Wave system (Oculus, Wetzlar, Germany), Anterion (Heidelberg Engineering GmBH, Heidelberg, Germany), and MS-39 (CSO, Florence, Italy) in ...
Gairik Kundu   +7 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

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