Tobacco dependence severity, cessation legacy and serial mediation in aging China. [PDF]
Tob Induc DisLi W, Liu M, Du W.
europepmc +1 more source
Summer Agricultural Program Activities [PDF]
Journal of Agricultural Education, 1997 openaire +1 more source
Advanced Science, EarlyView.Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li +13 more
wiley +1 more source
Design of a modular solver - Excel spreadsheet decision-support tool for calibrated nonlinear farm optimization in small holder farm systems. [PDF]
MethodsXZimuto W, Ahado S, Ratinger T, Spicka J.
europepmc +1 more source
Advanced Science, EarlyView.Tensile‐strained bismuth nanosheets (TS‐BiNs) achieve a formate Faradaic efficiency of 92% at −1000 mA cm−2 and enable stable production of pure formic acid (HCOOH) in a solid‐state electrolyte reactor. Theoretical calculations reveal that the introduced strain lowers the energy barrier for *OCHO intermediate formation, fundamentally enhancing the ...
Shiqi Li +16 more
wiley +1 more source
Beyond the Take-Home Pathway: Community-Level Pesticide Exposure Among Children Living in an Intensively Cultivated Agricultural Landscape. [PDF]
Int J Environ Res Public HealthGonzález H.
europepmc +1 more source
Advanced Science, EarlyView.This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi +13 more
wiley +1 more source
Understanding Farm Households' Tolerance Toward Asian Elephants in China: Evidence from 873 Households in Yunnan Province. [PDF]
Animals (Basel)Chen J, Xie Y, Zhang M, Lin W, Yang J.
europepmc +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
Advanced Science, EarlyView.This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Short-term crop rotation interactive effects on soil microbial communities and potato yield under field conditions. [PDF]
Front MicrobiolChiuta NE, Pofu KM, Mashela PW.
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