Results 41 to 50 of about 680,390 (262)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

open access: yesFEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki   +4 more
wiley   +1 more source

Occurrence of the Old World bug Megacopta cribraria (Fabricius) (Heteroptera: Plataspidae) in Georgia: a serious home invader and potential legume pest [PDF]

open access: yes, 2010
Specimens of Megacopta cribraria (Fabricius) were collected in northern Georgia in late October 2009, where they were invading homes in large numbers.
Ames, Lisa M.   +5 more
core  

Livelisystems: a conceptual framework integrating social, ecosystem, development and evolutionary theory [PDF]

open access: yes, 2014
Human activity poses multiple environmental challenges for ecosystems that have intrinsic value and also support that activity. Our ability to address these challenges is constrained, inter alia, by weaknesses in cross disciplinary understandings of ...
Dorward, Andrew
core   +2 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

open access: yesFEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer   +10 more
wiley   +1 more source

University students’ knowledge and attitudes towards leprosy

open access: yesJournal of Infection in Developing Countries, 2013
Introduction: Patients with leprosy may be affected psychologically and socially by the negative attitude of society toward leprosy, caused by widespread ignorance and prevailing stereotypes surrounding the disease.
Omar Graciano-Machuca   +3 more
doaj   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Why there was need of Asian Journal of Agriculture and Biology? [PDF]

open access: yesAsian Journal of Agriculture and Biology, 2013
Knowledge is exploding with every moment and science is discovering new horizons with every passing day. To encompass this knowledge and, particularly disseminate it to the scientific community free of cost, was the major inspiring force behind the ...
Zahid Iqbal
doaj  

Research collaboration between China and Denmark for development of systemic approaches to agro-ecological pest management without pesticides with focus on vegetable, fruit and berry crops. Proceedings and recommendations from two network workshops [PDF]

open access: yes, 2013
This report is the result of a network project which was established to discuss the potential for collaboration on development of systemic approaches to pest management without pesticides between Chinese and Danish researchers.
Andreasen, Lise   +16 more
core  

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Criteria to assess the interdisciplinary research development: an issue formulation

open access: yesБиблиосфера, 2018
Scientometric studies have become an integral part of scientific libraries activities with introducing the state rating system in Russian science. Scientometric studies contribute to study long-term trends in the science development, help to discover ...
Yu. D. Prokof’Eva
doaj   +1 more source

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