Results 41 to 50 of about 2,765,743 (308)

Preparation and interaction mechanism analysis of single-chain fragment variables against phenylethanolamine A

Animal Diseases
This is the first report on the screening, expression, and recognition mechanism analysis of single-chain fragment variable (scFv) against phenylethanolamine A (PEAA), a newly emerged β-adrenergic agonist illegally used as a feed additive for growth ...
Long Li, Ren Hou, Huaming Li, Shiyun Han, Jixiang Liang, Yu Si, Dapeng Peng   +6 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of Novel Thiazolidinone-Containing Quinoxaline-1,4-di-N-oxides as Antimycobacterial and Antifungal Agents

Frontiers in Chemistry, 2020
Tuberculosis and fungal infections can pose serious threats to human health. In order to find novel antimicrobial agents, 26 novel quinoxaline-1,4-di-N-oxides containing a thiazolidinone moiety were designed and synthesized, and their antimycobacterial ...
Heying Zhang, Heying Zhang, Jie Zhang, Jie Zhang, Wei Qu, Shuyu Xie, Lingli Huang, Lingli Huang, Dongmei Chen, Yanfei Tao, Zhenli Liu, Zhenli Liu, Yuanhu Pan, Yuanhu Pan, Zonghui Yuan, Zonghui Yuan   +15 more
doaj   +1 more source

Pesticide residues in food : report of the 1969 Joint Meeting of the FAO Working Party of Experts on Pesticide Residues and the WHO Expert Group on Pesticide Residues, Rome, 8-15 December 1969 [PDF]

, 1970
Russian version of nos. 454-488 bound together (barcode no.
World Health Organization, Food and Agriculture Organization of the United Nations, Joint Meeting of the FAO Working Party of Experts on Pesticide Residues and the WHO Expert Group on Pesticide Residues (1969: Rome)   +2 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Fangchinoline demonstrates efficacy against TGEV through pAPN binding, as determined by preliminary toxicity evaluation

Animal Diseases
Through structure-based virtual screening, this study identified the botanical compound fangchinoline (FAN) as an inhibitor of the porcine aminopeptidase N (pAPN) receptor and evaluated its anti-transmissible gastroenteritis virus (TGEV) activity ...
Siyi Hu, Mengping Song, Yulu Wang, Jieying Zhang, Defeng Wen, Yanan Liu, Juncheng Chen, Jiali Wu, Yanfei Tao, Xu Wang   +9 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Nanoparticles for treatment of bovine Staphylococcus aureus mastitis

Drug Delivery, 2020
Staphylococcus aureus (S. aureus) is one of the most important zoonotic bacterial pathogens, infecting human beings and a wide range of animals, in particular, dairy cattle. Globally. S.
Samah Attia Algharib, Ali Dawood, Shuyu Xie   +2 more
doaj   +1 more source

Valorisation of Agricultural Residues [PDF]

, 2016
[ES] El objetivo de la presente tesis doctoral es definir, desarrollar y evaluar una metodología eficiente de gestión de residuos, en particular agrícolas, para convertirlos en una nueva fuente de energía y en productos de valor añadido. Se estudia con especial atención el uso de la paja de arroz como vector energético y como precursor de productos ...
openaire   +2 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

The Spectrum of Antimicrobial Activity of Cyadox against Pathogens Collected from Pigs, Chicken, and Fish in China

Antibiotics, 2021
Cyadox has potential use as an antimicrobial agent in animals. However, its pharmacodynamic properties have not been systematically studied yet. In this study, the in vitro antibacterial activities of cyadox were assayed, and the antibacterial efficacy ...
Muhammad Kashif Maan, Zhifei Weng, Menghong Dai, Zhenli Liu, Haihong Hao, Guyue Cheng, Yulian Wang, Xu Wang, Lingli Huang   +8 more
doaj   +1 more source