Results 201 to 210 of about 1,688,884 (353)

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Correction: Editorial: Toxicity mechanisms, exposure, toxicokinetic and risk assessment aspects of metals, toxic for animals and humans, volume III. [PDF]

Front Pharmacol
Zhu Y, El Demerdash FM, Yang X, Machado MM, Boye A, Sun X.   +5 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Reply to Yang et al.: Synergies between photovoltaic development and innovative agricultural practices for combating desertification. [PDF]

Proc Natl Acad Sci U S A
Wang X, Geng X, Sun F, Han M, Liu F, Li C.   +5 more
europepmc   +1 more source

Homoisoflavanone Delays Colorectal Cancer Progression via DNA Damage‐Induced Mitochondrial Apoptosis and Parthanatos‐Like Cell Death

Advanced Science, EarlyView.
Homoisoflavanone (HIF), a bioactive compound isolated from Polygonatum kingianum, selectively suppresses colorectal cancer progression by inducing DNA damage‐mediated mitochondrial apoptosis and parthanatos‐like cell death. HIF triggers mitochondrial dysfunction, including depolarized membrane potential, elevated ROS, and ATP depletion, while impairing
Hongjie Fan, Huzi Zhao, Pei Zhang, Pengfei Yu, Yunfei Ji, Gang Chen, Hongli Jin, Yanfang Liu, Jin Liu, Zhe‐Sheng Chen, Aiping Lyu, Xinmiao Liang, Yang Chen   +12 more
wiley   +1 more source

A national-scale dataset of arable plant abundance from citizen science surveys of swedish field margins. [PDF]

Data Brief
Örnberg RC, Menegat A, Hickman DT, Auffret AG, Nilsson J, Nyborg G, Wikberg S, Andersson JY, Sundberg S.   +8 more
europepmc   +1 more source

Multivariate Analysis Applied to Forestry Agricultural Sciences: The Model-Directed Study [PDF]

, 2018
Angela Helena Silva Mendes Stival, Gilberto de Oliveira, Jéssica Bezerra Bandeira, Josué Luiz Marinho, Larissa da Silva Cintra, Patrícia Cardoso Dias, Debora Portella Biz, Augustus Caeser Franke Portella   +7 more
openalex   +1 more source

TheMudiame University, Irrua, Edo State (Undergraduate Admission Form) 2022/2023 STransfer Form is Out ☎  0806-591-2405- Prof Mrs.Aishat 08065912405 Post Utme Pre-Degree Form,Jupeb form, 08065912405, National Universities Commission (NUC) to run undergraduate programs in the Colleges of Agricultural Sciences; Sciences and Engineering, Business and Social Sciences. On March 21, 2011, the University was officially dedicated and commenced full operation.

, 2022
08065912405
openalex   +1 more source