Results 111 to 120 of about 5,815,563 (203)

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

Advanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li, Bohan Zhang, Chao Shang, Yi Li, Te Zhao, Shengya Liu, Dan Liu, Junwei Che, Cuiling Zhang, Pinghui Wu, Wenjie Yang, Junjie Ding, Yuhua Ran, Yanan Zhai, Haihua Xiao, Jing Gao, Xiao Li, Chunsheng Gao, Lin Li, Zhiping Li   +19 more
wiley   +1 more source

From awareness to action: determinants of zoonotic risk perception and protective practices among farm and livestock workers

Frontiers in Public Health
IntroductionZoonotic disease prevention among farm and livestock workers depends not only on awareness, but also on how workers perceive occupational risk and the feasibility of protective action.
Yong Shen Ooi, Yong Shen Ooi, Yong Shen Ooi, Norefrina Shafinaz Md Nor, Nur Azalina Suzianti Feisal, Nur Azalina Suzianti Feisal, Wai Yan Cheah, Wai Yan Cheah   +7 more
doaj   +1 more source

HIV and mobility in the Lake Victoria Basin agricultural sector: A literature review [PDF]

The Lake Victoria region has the highest HIV prevalence in the East African Community, which comprises Kenya, Uganda, Tanzania, Rwanda, and Burundi. This region also has a significant concentration of commercial agricultural plantations, which rely on ...
Wagah, Margaret, Gillespie, Stuart, Weinand, Julia, Drimie, Scott   +3 more
core  

Physiological Response of Agricultural Workers in Rice Farming Operations

, 2003
Physiological responses and energy expenditure of male and female agricultural workers in performing different rice farming operations were measured. The energy expenditure of male workers varied from 2.4 to 4.9 kcal/min whereas that of female workers ...
R Karunanithi, A Tajuddin
core   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

Advanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu, Wanlin Chen, Ben Cristofori‐Armstrong, Theo Crawford, Kai‐En Chen, Peng Xie, Rainbow Wing Bo Chan, Yifei Zhu, Mimi Golder, Anneka Pereira Schmidt, Jennifer D. Naughton, Nicholas D. Condon, Åsa Andersson, Farhad Dehkhoda, Kirsten L. McMahon, Tabea Klasfauseweh, Ashvriya Thapa, Hue Tran, Poanna Tran, Sina Jami, Lotten Ragnarsson, Sebastian G. B. Furness, Jennifer R. Deuis, Brett M. Collins, Wai‐Hong Tham, Indira Prasadam, Irina Vetter, Mehdi Mobli   +27 more
wiley   +1 more source

Effect of Extension Worker's Qualifications on The Performance of Agricultural Extension Workers in Agricultural Extension in Kendari City [PDF]

This research analyzed the state of extension worker's qualifications, the state of extension worker's performance, and the effect of qualifications on the performance of extension workers in Kendari City.
Salahuddin Salahuddin, Sukmawati Abdullah, Astuty Wunawarsih   +2 more
core   +1 more source

Sex‐ and Time‐Resolved Physiological and Gut Ecosystem Responses to a Food‐Grade Microbiome‐Targeted Intervention in Collegiate Endurance Athletes

Advanced Science, EarlyView.
In collegiate endurance athletes, a 6‐week randomized CPYE intervention yielded time‐ and sex‐dependent shifts in field‐based cardiorespiratory, metabolic, and redox indices, accompanied by changes in gut multi‐omics profiles. An exploratory extension during intensified training generates hypotheses warranting future validation.
Meng Zhang, Le Ge, Kaiyang Liu, Yanrong Liu, Guolin Zhao, Lai‐Yu Kwok, Zheng Sun, Zhihong Sun, Wenyi Zhang   +8 more
wiley   +1 more source

STRUCTURE OF PERIODONTAL TISSUE DISEASES IN WORKERS OF AGRICULTURAL PRODUCTION IN THE OPEN AND COVERED SOIL

Український стоматологічний альманах, 2018
Modern technological progress is characterized by comprehensive application of chemicals of the economy, including the widespread use of crop protection chemicals. Every year in Ukraine soils paid 1 million 700 thousand quintals of pesticides.
V.T. Dyryk
doaj  

Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt

Advanced Science, EarlyView.
A natural microbial consortium employing a cross‐feeding strategy forms a stratified biofilm that promotes endophytic colonization of auxotrophic Flavobacterium. This enhanced colonization activates plant systemic resistance, effectively suppressing Fusarium wilt.
Xianfeng Ye, Changsheng Xu, Shuai Yao, Jiming Shen, Zeyuan Li, Yu Zhang, Fan Wu, Xinjie Li, Yanling Ji, Lei Zhang, Yan Huang, Zhoukun Li, Huayu Qin, Zhongli Cui   +13 more
wiley   +1 more source