Results 281 to 290 of about 4,489,628 (313)

From Code to Life: The AI‐Driven Revolution in Genome Editing

open access: yesAdvanced Science, EarlyView.
This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li   +10 more
wiley   +1 more source

Malagasy integrated aquaculture-agriculture [PDF]

open access: yes, 2019
Andria-Mananjara, Diana Edithe   +6 more
core  

Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction

open access: yesAdvanced Science, EarlyView.
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod   +9 more
wiley   +1 more source

Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range

open access: yesAdvanced Science, EarlyView.
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen   +8 more
wiley   +1 more source

The Future of Vineyard Irrigation: AI-Driven Insights from IoT Data. [PDF]

open access: yesSensors (Basel)
Stojanova S   +4 more
europepmc   +1 more source

Characterisation of the genome and secretome of <i>Phytophthoracryptogea</i> and <i>P.erythroseptica</i>. [PDF]

open access: yesIMA Fungus
Hirooka Y   +6 more
europepmc   +1 more source

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