From Code to Life: The AI‐Driven Revolution in Genome Editing
This review explores AI‐driven advancements in genome editing, focusing on CRISPR optimization, enhanced targeting precision, reduced off‐target effects, and novel tool design. It addresses ethical challenges, data biases, and highlights future prospects in precision medicine, agriculture, and synthetic biology.
Zhidong Li+10 more
wiley +1 more source
Editorial: Innovative strategies for enhancing plant resilience to phytopathogenic microbes. [PDF]
Ahmed T, Janssen D, Nehela Y.
europepmc +1 more source
Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod+9 more
wiley +1 more source
Assessment of water hyacinth (Pontederia crassipes) distribution and changes in Lake Koka and Lake Ziway through remote sensing techniques. [PDF]
Tolera G+3 more
europepmc +1 more source
Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen+8 more
wiley +1 more source
The Future of Vineyard Irrigation: AI-Driven Insights from IoT Data. [PDF]
Stojanova S+4 more
europepmc +1 more source
Characterisation of the genome and secretome of <i>Phytophthoracryptogea</i> and <i>P.erythroseptica</i>. [PDF]
Hirooka Y+6 more
europepmc +1 more source
Resilience to abrupt global catastrophic risks disrupting trade: Combining urban and near-urban agriculture in a quantified case study of a globally median-sized city. [PDF]
Boyd M, Wilson N.
europepmc +1 more source