Results 31 to 40 of about 322 (188)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Rooting for food security in Sub-Saharan Africa

open access: yesEnvironmental Research Letters, 2017
There is a persistent narrative about the potential of Sub-Saharan Africa (SSA) to be a ‘grain breadbasket’ because of large gaps between current low yields and yield potential with good management, and vast land resources with adequate rainfall. However,
Nicolas Guilpart   +9 more
doaj   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Réponse du maïs ensilage (Zea mays L.) aux époques d'apport du Zinc dans le sol sablonneux du Loukkos (Nord-Ouest du Maroc)

open access: yesRevue Marocaine des Sciences Agronomiques et Vétérinaires, 2015
L’influence de l’époque d’apport au sol du Zinc (Zn) sur la croissance, le rendement et le statut nutritif en Zn du maïs ensilage a été étudiée au niveau du sol sablonneux du Loukkos. Cinq époques d’apport au sol de 5 mg/kg du Zn ont été testées au sein
Saad DRISSI   +4 more
doaj  

Economic hurdles, social gains: unveiling the true motivations behind urban farming

open access: yesCogent Food & Agriculture
This study examined the social and economic feasibility of urban farming in Bandung, Indonesia, from the viewpoint of the actors. Observations, semi-structured and in-depth interviews with key informants including urban farmers, urban farming community ...
Adi Nugraha   +5 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

Mungbean [Vigna radiata (L.) Wilczek] and its potential for crop diversification and sustainable food production in Sub-Saharan Africa: a review

open access: yesTechnology in Agronomy
Mungbean [Vigna radiata (L.) Wilczek] is an important tropical legume mainly cultivated in South and East Asia but remains a minor grain legume in Sub-Sahara Africa (SSA).
Andre A. Diatta   +6 more
doaj   +1 more source

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