Results 41 to 50 of about 204,751 (311)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

1970 virus ratings for corn strains in Missouri [PDF]

open access: yes, 1970
Cover title."This Special Report is a contribution from the Departments of Agronomy and Entomology, University of Missouri Agricultural Experiment Station, projects 3770 and 145; and Crops Research Division, Agricultural Research Service, U.S. Department
Zuber, M. S. (Marcus Stanley), 1912-1998.
core  

Managing soil fertility in organic farming systems [PDF]

open access: yes, 2002
Complex relationships exist between different components of the organic farm and the quantity and quality of the end products depend on the functioning of the whole system.
Abawi   +106 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Effects of different phosphorus and potassium supply on the root architecture, phosphorus and potassium uptake, and utilization efficiency of hydroponic rice

open access: yesScientific Reports
Phosphorus (P) and potassium (K) affect seedling growth, root configuration, and nutrient uptake in hydroponic rice, but there are few studies on all growth stages of rice.
Ya Liu   +7 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Enlightened Interaction between Agronomy and Agricultural Economics [PDF]

open access: yesJournal of Production Agriculture, 1990
This paper looks at a future in which both disciplines are coping with a declining clientele and support base. It asks the question: Are there ways that we all can better cope with our problems by working together? The concepts of systems analysis and holistic management are considered as a basis for multi‐disciplinary work.
openaire   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Worldwide Research Trends on Wheat and Barley: A Bibliometric Comparative Analysis [PDF]

open access: yes, 2019
Grain cereals such as wheat, barley, rice, and maize are the nutritional basis of humans and animals worldwide. Thus, these crop plants are essential in terms of global food security.
Benavente Barzana, María Elena   +3 more
core   +1 more source

Responses of different panicum miliaceum l. Genotypes to saline and water stress in a marginal mediterranean environment [PDF]

open access: yes, 2018
The aims of this study were to evaluate: (1) the effect of sodium chloride (NaCl) and mannitol at different osmotic pressures on the germination of three proso millet (Panicum miliaceum L.) genotypes (VIR 9181, Unikum, and Kinelskoje) under controlled ...
Aggarwal   +12 more
core   +2 more sources

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