This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li +7 more
wiley +1 more source
Correction: Dysregulated interferon signaling and hyperinflammation upon <i>FCGBP</i> knockdown in goat bronchial epithelial cells infected with <i>Pasteurella multocida</i>. [PDF]
Yang Y +8 more
europepmc +1 more source
NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang +10 more
wiley +1 more source
Understanding policy alignment in addressing hydrological hazards in the Niger Delta region, Nigeria. [PDF]
Agumagu OO, Marchant R, Stringer LC.
europepmc +1 more source
Climate change reshapes the spatial alignment between crop production and environmental resources. Using multi‐source data and a crop model, integrated climatic, water, and soil endowments for maize and wheat are quantified and compared with harvest distributions.
Zheng'e Su +13 more
wiley +1 more source
Correction: <i>Candidatus</i> Liberibacter asiaticus encodes a functional BolA transcriptional regulator related to motility, biofilm development, and stress response. [PDF]
Zhan X +6 more
europepmc +1 more source
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun +5 more
wiley +1 more source
Special section on interstitial lung disease in domestic animals. [PDF]
Carvallo-Chaigneau FR, Caswell JL.
europepmc +1 more source
Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen +7 more
wiley +1 more source
Peat cutaway properties define after-use options and capacity for climate regulation. [PDF]
Maanavilja L +5 more
europepmc +1 more source

