Results 41 to 50 of about 871,528 (311)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Speeding up innovation in agricultural IT

Journal of Agricultural Engineering, 2013
An OECD funded research was conducted where methods and processes for speeding up innovation in agriculture were assessed. A global web-based questionnaire was sent to experts in agricultural engineering, research, marketing, education and users of new ...
Hannu E.S. Haapala
doaj   +1 more source

Climate-Smart Agriculture: What is it? Why is it needed? [PDF]

, 2015
In the next 20 years, increasing the productivity and incomes from smallholder crop, livestock, fishery and forestry production systems will be key to achieving global food security.
CGIAR Research Program on Climate Change, Agriculture and Food Security, Food and Agriculture Organization of the United Nations   +1 more
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Agricultural competitiveness white paper: stronger farmers, stronger economy [PDF]

, 2015
In this white paper the Federal Government sets out the environment needed to drive better returns for farmers, increase investment, job creation, stronger regional communities and economic growth.
Department of Agriculture (Australia)
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Genome-wide characterization of the soybean DOMAIN OF UNKNOWN FUNCTION 679 membrane protein gene family highlights their potential involvement in growth and stress response

Frontiers in Plant Science, 2023
The DMP (DUF679 membrane proteins) family is a plant-specific gene family that encodes membrane proteins. The DMP family genes are suggested to be involved in various programmed cell death processes and gamete fusion during double fertilization in ...
Bhagwat Nawade, Bhagwat Nawade, Tejas C. Bosamia, Jae Hyun Lee, Jae Hyun Lee, Jin Hoon Jang, Jin Hoon Jang, Ok Ran Lee, Ok Ran Lee   +8 more
doaj   +1 more source

Agriculture industrielle et agriculture industrialisée (Industrial agriculture and industrialized agriculture)

Bulletin de l'Association de géographes français, 1988
Résumé. - De nombreuses exploitations agricoles sont aujourd'hui considérées comme «industrielles». L'article dénonce remploi abusif de ce qualificatif qui devrait être réservé à certains cas exceptionnels, et établit la distinction entre une agriculture «industrielle » (ayant les caractères de l'industrie) et une agriculture «industrialisée » (qui ...
openaire   +2 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source