Results 111 to 120 of about 15,005 (289)

Ring Formation in Sesquiterpene Synthesis: Biomimetic vs. Non‐Biomimetic Strategies

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A short review of cyclase enzyme‐mediated ring formation in sesquiterpene biosynthesis is presented as a prelude to six case studies examining the merits and demerits of biomimetic vs. non‐biomimetic strategies for carbocyclisation in the total synthesis of this iconic natural product class.
Bohan Lin, Chen Dai, Alan C. Spivey
wiley   +1 more source

Pt Sub‐Nanoclusters on ZIF‐Derived Ultrafine CdxZn1−xS Solid Solution: High‐Performance Photoreforming Lactic Acid to H2 and Value‐Added Chemicals

open access: yesElectron, EarlyView.
This work presents ZIF‐derived ultrafine CdxZn1−xS decorated with Pt sub‐nanoclusters for efficient photocatalytic reforming of lactic acid. The catalyst achieves high H2 evolution (270.6 mmol h−1 g−1) and selective pyruvic acid production (73.1%), with mechanistic insights revealing Pt‐mediated control over reaction pathways.
Feng Liu   +5 more
wiley   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk   +4 more
wiley   +1 more source

Evaluation of the standard battery of in vitro genotoxicity tests to predict in vivo genotoxicity through mathematical modeling: A report from the 8th International Workshop on Genotoxicity Testing

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract In human health risk assessment of chemicals and pharmaceuticals, identification of genotoxicity hazard usually starts with a standard battery of in vitro genotoxicity tests, which is needed to cover all genotoxicity endpoints. The individual tests included in the battery are not designed to pick up all endpoints.
Mirjam Luijten   +15 more
wiley   +1 more source

Consensus findings of an International Workshops on Genotoxicity Testing workshop on using transcriptomic biomarkers to predict genotoxicity

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Gene expression biomarkers have the potential to identify genotoxic and non‐genotoxic carcinogens, providing opportunities for integrated testing and reducing animal use. In August 2022, an International Workshops on Genotoxicity Testing (IWGT) workshop was held to critically review current methods to identify genotoxicants using ...
Roland Froetschl   +14 more
wiley   +1 more source

Recent Advances in Conjugated Microporous Polymers for Photocatalysis: Mechanism, Synthesis and Applications

open access: yesExploration, EarlyView.
Conjugated microporous polymers (CMPs) have attracted more and more attention as new photocatalysts due to their unique advantages such as high performance, long stability and strong light absorption. This review summarizes the application of CMPs as a photocatalyst in recent years and introduces the catalytic mechanism.
Dun Zhou   +5 more
wiley   +1 more source

AGROCHEMICAL AND BIOLOGICAL PROPERTIES OF IRRIGATED GRAY SOILS

open access: green, 2023
Xolmo'minov Samandar Murodjon o'g'li Gapparov Islom Uchqun o'g'li
openalex   +1 more source

Electron Donor–Acceptor Complexes Without Preinstalled Sacrificial Leaving Groups: Applications in Synthesis

open access: yesHelvetica Chimica Acta, EarlyView.
Leaving‐group–free electron donor–acceptor (EDA) complexes have emerged as a practical platform for photocatalyst‐free radical generation under visible light. This review highlights recent advances in coupling and cyclization reactions driven by such EDA complexes, emphasizing their atom‐economical and sustainable feature.
Wenheng Liu, Line Næsborg
wiley   +1 more source

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