Results 151 to 160 of about 36,347 (337)

Rewriting Alkene Frameworks: A Practical Strategy for Nitrogen Incorporation

open access: yesChemistryEurope, EarlyView.
Morandi and team developed a metal‐free method to insert nitrogen into unactivated alkenes, forming amidines and nitriles via a transient aza‐allenium intermediate. Using mild, open‐flask conditions, the process delivers high yields and broad functional group tolerance.
Ranjini Laskar, Frank Glorius
wiley   +1 more source

Boronate‐Type‐Controlled Regioselective Catalytic [2 + 2 + 2] Cyclotrimerization for Synthesis of Polysubstituted 2‐ and 3‐Borylated Pyridines

open access: yesChemistryEurope, EarlyView.
Ring the boron, not the bell: cyclotrimerization of borylated diynes with nitriles using Co and Ru catalysts allows the efficient synthesis of a wide variety of borylated pyridines with high regioselectivity, paving the way for multiple post‐functionalizations.
Eva Bednářová   +7 more
wiley   +1 more source

Nitrogen‐Centered Radical‐Directed C(sp3)−H Amination and Aminoalkylation Using (Diarylmethylene)amino Benziodoxolones

open access: yesChemistryEurope, EarlyView.
This report describes a C(sp3)−H aminofunctionalization via the photoexcitation of (diarylmethylene)amino benziodoxolones. These iodine reagents act as both single‐electron oxidants and nitrogen‐based SOMOphiles, serving as iminyl radicals, enabling the site‐selective C(sp3)−H amination and aminoalkylation of α‐aminoxy acid derivatives.
Kensuke Kiyokawa   +5 more
wiley   +1 more source

Synthesis of Cyclic Sulfilimines and Sulfoximines via Copper‐Mediated C(sp2)–H Sulfanylation of Benzylamines with a Catalytic Transient Directing Group

open access: yesChemistryEurope, EarlyView.
Copper‐mediated transient C─H sulfanylation of benzylamines with sulfenamides enables rapid access to thioethers, cyclic sulfilimines, and sulfoximines. Mechanistic investigations using 1H NMR and electron paramagnetic resonance spectroscopy reveal an unprecedented thermally induced homolytic cleavage of the sulfenamide N─S bond, slowly releasing the ...
Tsz‐Kan Ma   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy